Gene description for ARSG
Gene name arylsulfatase G
Gene symbol ARSG
Other names/aliases -
Species Homo sapiens
 Database cross references - ARSG
ExoCarta ExoCarta_22901
Vesiclepedia VP_22901
Entrez Gene 22901
HGNC 24102
MIM 610008
UniProt Q96EG1  
 ARSG identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for ARSG
Molecular Function
    arylsulfatase activity GO:0004065 IDA
    arylsulfatase activity GO:0004065 IDA
    arylsulfatase activity GO:0004065 IMP
    arylsulfatase activity GO:0004065 TAS
    N-sulfoglucosamine-3-sulfatase activity GO:0033889 IDA
    metal ion binding GO:0046872 IEA
Biological Process
    sulfur compound metabolic process GO:0006790 IDA
    lysosome organization GO:0007040 IEA
    glial cell differentiation GO:0010001 IEA
    gene expression GO:0010467 IEA
    homeostasis of number of cells GO:0048872 IEA
    neuron apoptotic process GO:0051402 IEA
    retina development in camera-type eye GO:0060041 IEA
Subcellular Localization
    extracellular space GO:0005615 IDA
    lysosome GO:0005764 IDA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum lumen GO:0005788 TAS
 Experiment description of studies that identified ARSG in sEVs
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ARSG
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LYZL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 TOR3A 64222
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 MESDC2 23184
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 CTAGE5 4253
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 DPH1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 CANX 821
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 HLA-G 3135
Affinity Capture-MS Homo sapiens
8 TMEM214 54867
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 DUS3L 56931
Affinity Capture-MS Homo sapiens
10 FBXO21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 TRGV3  
Affinity Capture-MS Homo sapiens
12 PDGFRA 5156
Affinity Capture-MS Homo sapiens
13 TUBB8 347688
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 IL5RA  
Affinity Capture-MS Homo sapiens
15 GSK3A 2931
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 APEX1 328
Affinity Capture-RNA Homo sapiens
17 IDE 3416
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 TUBA4A 7277
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 EMR4P  
Affinity Capture-MS Homo sapiens
20 TM2D3  
Affinity Capture-MS Homo sapiens
21 ADAMTS12 81792
Affinity Capture-MS Homo sapiens
22 CGRRF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 FBXO3  
Affinity Capture-MS Homo sapiens
24 FAM69A 388650
Affinity Capture-MS Homo sapiens
25 TRIM21 6737
Affinity Capture-MS Homo sapiens
26 BACE2 25825
Affinity Capture-MS Homo sapiens
27 PSCA 8000
Affinity Capture-MS Homo sapiens
28 B3GAT2  
Affinity Capture-MS Homo sapiens
29 PTPRK 5796
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 SUMF1 285362
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 YDJC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 QRSL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 SPCS1 28972
Affinity Capture-MS Homo sapiens
34 EIF2AK3  
Affinity Capture-MS Homo sapiens
35 LIPG 9388
Affinity Capture-MS Homo sapiens
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