Gene description for IL17RC
Gene name interleukin 17 receptor C
Gene symbol IL17RC
Other names/aliases IL17-RL
IL17RL
Species Homo sapiens
 Database cross references - IL17RC
ExoCarta ExoCarta_84818
Vesiclepedia VP_84818
Entrez Gene 84818
HGNC 18358
MIM 610925
UniProt Q8NAC3  
 IL17RC identified in exosomes derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for IL17RC
Molecular Function
    signaling receptor binding GO:0005102 IEA
    protein binding GO:0005515 IPI
    coreceptor activity GO:0015026 IDA
    interleukin-17 receptor activity GO:0030368 IBA
    interleukin-17 receptor activity GO:0030368 IDA
Biological Process
    inflammatory response GO:0006954 IEA
    positive regulation of interleukin-6 production GO:0032755 IEA
    interleukin-17A-mediated signaling pathway GO:0038173 IDA
    defense response to fungus GO:0050832 IEA
    granulocyte chemotaxis GO:0071621 IEA
    positive regulation of cytokine production involved in inflammatory response GO:1900017 IEA
Subcellular Localization
    plasma membrane GO:0005886 IC
    plasma membrane GO:0005886 TAS
    cell surface GO:0009986 IEA
 Experiment description of studies that identified IL17RC in exosomes
1
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IL17RC
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 C2CD2L 9854
Affinity Capture-MS Homo sapiens
2 ADCY3 109
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 MR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 ENPP4 22875
Affinity Capture-MS Homo sapiens
5 PLXNB2 23654
Affinity Capture-MS Homo sapiens
6 TRAF3IP2  
Affinity Capture-Western Homo sapiens
7 DISP1 84976
Affinity Capture-MS Homo sapiens
8 AMZ2  
Affinity Capture-MS Homo sapiens
9 TMBIM6 7009
Affinity Capture-MS Homo sapiens
10 C1orf43 25912
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 GMCL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 RNF167 26001
Affinity Capture-MS Homo sapiens
13 HSPA8 3312
Affinity Capture-MS Homo sapiens
14 PDZD8 118987
Affinity Capture-MS Homo sapiens
15 MANEAL 149175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 TYW1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 ECEL1  
Affinity Capture-MS Homo sapiens
18 ADCK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 NPC1 4864
Affinity Capture-MS Homo sapiens
20 PDE3B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 HERC3 8916
Affinity Capture-MS Homo sapiens
22 LRP12 29967
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 MBTPS2  
Affinity Capture-MS Homo sapiens
24 MAP3K7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 ARL8B 55207
Affinity Capture-MS Homo sapiens
26 FADS1 3992
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 TMEM39A  
Affinity Capture-MS Homo sapiens
28 GYLTL1B 120071
Affinity Capture-MS Homo sapiens
29 BAG6 7917
Affinity Capture-MS Homo sapiens
30 KCNJ11  
Affinity Capture-MS Homo sapiens
31 CHST10  
Affinity Capture-MS Homo sapiens
32 ABCA3 21
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 ITGA7 3679
Affinity Capture-MS Homo sapiens
34 SREBF2 6721
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 GET4 51608
Affinity Capture-MS Homo sapiens
36 FAM69A 388650
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 EPHA7 2045
Affinity Capture-MS Homo sapiens
38 KCNT2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 TAB2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 ABHD3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 LMF2 91289
Affinity Capture-MS Homo sapiens
42 DHRS3 9249
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 SLC12A4 6560
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 ACVR2B  
Affinity Capture-MS Homo sapiens
45 ATP2A3 489
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 ALG9 79796
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 MAN2A2 4122
Affinity Capture-MS Homo sapiens
48 PIGQ  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 EPHB4 2050
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 KIAA0922  
Affinity Capture-MS Homo sapiens
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