Experiment description of studies that identified MANEAL in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for MANEAL

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SLC39A12   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 ST8SIA3   Affinity Capture-MS Homo sapiens 3 CSGALNACT2 55454 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 NAAA   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 CEACAM8 1088 Affinity Capture-MS Homo sapiens 6 CHRNA4   Affinity Capture-MS Homo sapiens 7 TTYH1   Affinity Capture-MS Homo sapiens 8 SIAE 54414 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 TMPRSS11B 132724 Affinity Capture-MS Homo sapiens 10 PEX19 5824 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 CCL3   Affinity Capture-MS Homo sapiens 12 HPN   Affinity Capture-MS Homo sapiens 13 MME 4311 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 ADAM33 80332 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 15 ASIC4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 16 HTR3C   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 17 HS3ST2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 GGT7 2686 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 ATP1B3 483 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 SLC22A9   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 21 PCDHB11   Affinity Capture-MS Homo sapiens 22 CLEC12B   Affinity Capture-MS Homo sapiens 23 ST3GAL4 6484 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 SAAL1 113174 Affinity Capture-MS Homo sapiens 25 GAA 2548 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 IDS   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 27 SCGB2A2   Affinity Capture-MS Homo sapiens 28 C1orf54   Affinity Capture-MS Homo sapiens 29 PSCA 8000 Affinity Capture-MS Homo sapiens 30 BCHE 590 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 31 PLXDC2 84898 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 IL17RC 84818 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 33 PSG8   Affinity Capture-MS Homo sapiens 34 TMPRSS13   Affinity Capture-MS Homo sapiens View the network

Pathways in which MANEAL is involved

No pathways found