Gene description for RPP30
Gene name ribonuclease P/MRP 30kDa subunit
Gene symbol RPP30
Other names/aliases TSG15
Species Homo sapiens
 Database cross references - RPP30
ExoCarta ExoCarta_10556
Entrez Gene 10556
HGNC 17688
MIM 606115
UniProt P78346  
 RPP30 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for RPP30
Molecular Function
    protein binding GO:0005515 IPI
    ribonuclease P activity GO:0004526 IEA
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    tRNA processing GO:0008033 IBA
    RNA phosphodiester bond hydrolysis GO:0090501 TAS
    RNA phosphodiester bond hydrolysis, endonucleolytic GO:0090502 TAS
Subcellular Localization
    nucleus GO:0005634 TAS
    nucleolar ribonuclease P complex GO:0005655 TAS
 Experiment description of studies that identified RPP30 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPP30
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 POP1 10940
Two-hybrid Homo sapiens
2 RPP14  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
3 POP4 10775
Two-hybrid Homo sapiens
4 RPP21  
Two-hybrid Homo sapiens
5 RPP40  
Invivo Homo sapiens
6 RPP38  
Invivo Homo sapiens
7 POP7  
Invivo Homo sapiens
View the network image/svg+xml
 Pathways in which RPP30 is involved
No pathways found





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