Gene description for MEX3C
Gene name mex-3 RNA binding family member C
Gene symbol MEX3C
Other names/aliases BM-013
MEX-3C
RKHD2
RNF194
Species Homo sapiens
 Database cross references - MEX3C
ExoCarta ExoCarta_51320
Entrez Gene 51320
HGNC 28040
MIM 611005
UniProt Q5U5Q3  
 MEX3C identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for MEX3C
Molecular Function
    ligase activity GO:0016874 IEA
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IEA
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    regulation of fat cell differentiation GO:0045598 IEA
    energy homeostasis GO:0097009 IEA
    chondrocyte hypertrophy GO:0003415 IEA
    metabolic process GO:0008152 IEA
    activation of mitophagy in response to mitochondrial depolarization GO:0098779 IMP
Subcellular Localization
    cytoplasm GO:0005737 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified MEX3C in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for MEX3C
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MEX3C is involved
No pathways found





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