Gene description for CNOT1
Gene name	CCR4-NOT transcription complex, subunit 1
Gene symbol	CNOT1
Other names/aliases	AD-005 CDC39 NOT1 NOT1H
Species	Homo sapiens
Database cross references - CNOT1
ExoCarta	ExoCarta_23019
Entrez Gene	23019
HGNC	7877
MIM	604917
UniProt	A5YKK6
CNOT1 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Thymus	23844026

Gene ontology annotations for CNOT1

Molecular Function     armadillo repeat domain binding GO:0070016 IPI     protein domain specific binding GO:0019904 IPI     protein binding GO:0005515 IPI     protein complex scaffold GO:0032947 IDA     estrogen receptor binding GO:0030331 IDA     poly(A)-specific ribonuclease activity GO:0004535 IDA     poly(A) RNA binding GO:0044822 IDA     retinoic acid receptor binding GO:0042974 IDA Biological Process     positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900153 IMP     transcription, DNA-templated GO:0006351 IEA     nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 TAS     gene expression GO:0010467 TAS     negative regulation of retinoic acid receptor signaling pathway GO:0048387 IDA     regulation of stem cell maintenance GO:2000036 IMP     nuclear-transcribed mRNA poly(A) tail shortening GO:0000289 TAS     positive regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:0060213 IMP     positive regulation of mRNA catabolic process GO:0061014 IMP     RNA phosphodiester bond hydrolysis, exonucleolytic GO:0090503 IDA     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IDA     negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 IDA     negative regulation of translation GO:0017148 IDA     multicellular organismal development GO:0007275 IEA     gene silencing by miRNA GO:0035195 IDA     positive regulation of cytoplasmic mRNA processing body assembly GO:0010606 IDA Subcellular Localization     extracellular space GO:0005615 IDA     peroxisomal membrane GO:0005778 IDA     nucleoplasm GO:0005654 IDA     membrane GO:0016020 IDA     cytoplasmic mRNA processing body GO:0000932 ISS     CCR4-NOT complex GO:0030014 IDA     cytosol GO:0005829 TAS