Gene description for LGR4
Gene name	leucine-rich repeat containing G protein-coupled receptor 4
Gene symbol	LGR4
Other names/aliases	BNMD17 GPR48
Species	Homo sapiens
Database cross references - LGR4
ExoCarta	ExoCarta_55366
Entrez Gene	55366
HGNC	13299
MIM	606666
UniProt	Q9BXB1
LGR4 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for LGR4

Molecular Function     transmembrane signaling receptor activity GO:0004888 IDA     protein binding GO:0005515 IPI     G-protein coupled receptor activity GO:0004930 IDA Biological Process     negative regulation of toll-like receptor signaling pathway GO:0034122 ISS     bone mineralization GO:0030282 ISS     epithelial cell proliferation GO:0050673 IEA     G-protein coupled receptor signaling pathway GO:0007186 IEA     osteoblast differentiation GO:0001649 ISS     metanephric nephron tubule morphogenesis GO:0072282 IEA     innate immune response GO:0045087 IEA     negative regulation of transcription, DNA-templated GO:0045892 IEA     male genitalia development GO:0030539 IEA     cell differentiation involved in metanephros development GO:0072202 IEA     metanephric glomerulus development GO:0072224 IEA     canonical Wnt signaling pathway involved in metanephric kidney development GO:0061290 IEA     spermatogenesis GO:0007283 ISS     negative regulation of cytokine secretion GO:0050710 ISS     positive regulation of canonical Wnt signaling pathway GO:0090263 IDA     circadian regulation of gene expression GO:0032922 ISS     positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 IEA     bone remodeling GO:0046849 ISS     positive regulation of transcription, DNA-templated GO:0045893 IEA Subcellular Localization     integral component of plasma membrane GO:0005887 IDA     plasma membrane GO:0005886 TAS