Gene description for NPC1L1 |
Gene name |
NPC1-like 1 |
Gene symbol |
NPC1L1 |
Other names/aliases |
NPC11L1 |
Species |
Homo sapiens |
Database cross references - NPC1L1 |
ExoCarta |
ExoCarta_29881 |
Vesiclepedia |
VP_29881 |
Entrez Gene |
29881 |
HGNC |
7898 |
MIM |
608010 |
UniProt |
Q9UHC9
|
NPC1L1 identified in exosomes derived from the following tissue/cell type |
Pancreatic duct fluid
|
29339034
|
Pancreatic duct fluid
|
29339034
|
Gene ontology annotations for NPC1L1 |
|
Experiment description of studies that identified NPC1L1 in exosomes |
1 |
Experiment ID |
622 |
MISEV standards |
✔
EM
|
Biophysical techniques |
|
Enriched markers |
✔
GOLGA2|CYC1
|
Negative markers |
✔
NTA
|
Particle analysis
|
|
Identified molecule |
Protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
29339034
|
Organism |
Homo sapiens |
Experiment description |
Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer |
Authors |
"Zheng J, Hernandez JM, Doussot A, Bojmar L, Zambirinis CP, Costa-Silva B, van Beek EJAH, Mark MT, Molina H, Askan G, Basturk O, Gonen M, Kingham TP, Allen PJ, D'Angelica MI, DeMatteo RP, Lyden D, Jarnagin WR." |
Journal name |
HPB
|
Publication year |
2018 |
Sample |
Pancreatic duct fluid |
Sample name |
From patients with Pancreatic ductal adenocarcinoma |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
2 |
Experiment ID |
623 |
MISEV standards |
✘
|
Biophysical techniques |
|
Enriched markers |
✔
GOLGA2|CYC1
|
Negative markers |
✔
NTA
|
Particle analysis
|
|
Identified molecule |
Protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
29339034
|
Organism |
Homo sapiens |
Experiment description |
Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer |
Authors |
"Zheng J, Hernandez JM, Doussot A, Bojmar L, Zambirinis CP, Costa-Silva B, van Beek EJAH, Mark MT, Molina H, Askan G, Basturk O, Gonen M, Kingham TP, Allen PJ, D'Angelica MI, DeMatteo RP, Lyden D, Jarnagin WR." |
Journal name |
HPB
|
Publication year |
2018 |
Sample |
Pancreatic duct fluid |
Sample name |
From patients with IPMN with microinvasive cancer (IPMNca) |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
Protein-protein interactions for NPC1L1 |
|
Pathways in which NPC1L1 is involved |
|
|
|