Gene description for NUP210
Gene name nucleoporin 210kDa
Gene symbol NUP210
Other names/aliases GP210
POM210
Species Homo sapiens
 Database cross references - NUP210
ExoCarta ExoCarta_23225
Entrez Gene 23225
HGNC 30052
MIM 607703
UniProt Q8TEM1  
 NUP210 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for NUP210
Molecular Function
    protein dimerization activity GO:0046983 IEA
Biological Process
    hexose transport GO:0008645 TAS
    glucose transport GO:0015758 TAS
    viral process GO:0016032 TAS
    cellular response to heat GO:0034605 TAS
    transmembrane transport GO:0055085 TAS
    cellular protein metabolic process GO:0044267 TAS
    viral life cycle GO:0019058 TAS
    mitotic nuclear envelope disassembly GO:0007077 TAS
    cytokine-mediated signaling pathway GO:0019221 TAS
    regulation of glucose transport GO:0010827 TAS
    protein transport GO:0015031 IEA
    viral transcription GO:0019083 TAS
    mRNA transport GO:0051028 IEA
    mitotic cell cycle GO:0000278 TAS
    gene expression GO:0010467 TAS
    regulation of cellular response to heat GO:1900034 TAS
    small molecule metabolic process GO:0044281 TAS
    post-translational protein modification GO:0043687 TAS
    carbohydrate metabolic process GO:0005975 TAS
    protein sumoylation GO:0016925 TAS
Subcellular Localization
    nuclear pore GO:0005643 IEA
    nuclear membrane GO:0031965 IEA
    endoplasmic reticulum membrane GO:0005789 IEA
    nuclear envelope GO:0005635 TAS
    membrane GO:0016020 IDA
 Experiment description of studies that identified NUP210 in exosomes
1
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NUP210
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TRIP6  
Two-hybrid Homo sapiens
2 EXOSC5 56915
Two-hybrid Homo sapiens
View the network image/svg+xml



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