Gene description for MEX3B
Gene name mex-3 RNA binding family member B
Gene symbol MEX3B
Other names/aliases MEX-3B
RKHD3
RNF195
Species Homo sapiens
 Database cross references - MEX3B
ExoCarta ExoCarta_84206
Entrez Gene 84206
HGNC 25297
MIM 611008
UniProt Q6ZN04  
 MEX3B identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for MEX3B
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    calcium ion binding GO:0005509 ISS
    zinc ion binding GO:0008270 IEA
Biological Process
    protein phosphorylation GO:0006468 ISS
    protein autophosphorylation GO:0046777 ISS
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    cytoplasmic mRNA processing body GO:0000932 IEA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified MEX3B in exosomes
1
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MEX3B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RAP1GAP 5909
Two-hybrid Homo sapiens
2 UBE2D3 7323
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which MEX3B is involved
No pathways found





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