Gene description for MEX3B
Gene name mex-3 RNA binding family member B
Gene symbol MEX3B
Other names/aliases MEX-3B
RKHD3
RNF195
Species Homo sapiens
 Database cross references - MEX3B
ExoCarta ExoCarta_84206
Vesiclepedia VP_84206
Entrez Gene 84206
HGNC 25297
MIM 611008
UniProt Q6ZN04  
 MEX3B identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for MEX3B
Molecular Function
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IDA
    calcium ion binding GO:0005509 ISS
    protein binding GO:0005515 IPI
Biological Process
    protein phosphorylation GO:0006468 ISS
    protein autophosphorylation GO:0046777 ISS
Subcellular Localization
    P-body GO:0000932 IDA
    nucleoplasm GO:0005654 IDA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified MEX3B in exosomes
1
Experiment ID 191
MISEV standards
Biophysical techniques
Alix|CD81|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MEX3B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 YWHAH 7533
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
2 RAP1GAP 5909
Two-hybrid Homo sapiens
3 WDR6 11180
Affinity Capture-MS Homo sapiens
4 MYCN  
Affinity Capture-MS Homo sapiens
5 CFLAR  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
6 PRPF8 10594
Affinity Capture-MS Homo sapiens
7 AGO1  
Affinity Capture-Western Homo sapiens
8 YWHAB 7529
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 LINC00839  
Protein-RNA Homo sapiens
10 ATP13A2  
Two-hybrid Homo sapiens
11 ENPP6 133121
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 CUL3 8452
Affinity Capture-MS Homo sapiens
13 YWHAZ 7534
Affinity Capture-MS Homo sapiens
14 MEX3C 51320
Affinity Capture-MS Homo sapiens
15 RUNX3  
Affinity Capture-Western Homo sapiens
16 PIP4K2A 5305
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 GID8 54994
Affinity Capture-MS Homo sapiens
18 PABPC1 26986
Affinity Capture-Western Homo sapiens
19 YWHAE 7531
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 MEX3D  
Affinity Capture-MS Homo sapiens
21 HOTAIR  
Affinity Capture-RNA Homo sapiens
22 NUDT3 11165
Two-hybrid Homo sapiens
23 UBE2D3 7323
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
24 YWHAG 7532
Affinity Capture-MS Homo sapiens
25 SNUPN 10073
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
View the network image/svg+xml
 Pathways in which MEX3B is involved
No pathways found





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