Gene description for SNRPA1
Gene name small nuclear ribonucleoprotein polypeptide A'
Gene symbol SNRPA1
Other names/aliases Lea1
Species Homo sapiens
 Database cross references - SNRPA1
ExoCarta ExoCarta_6627
Entrez Gene 6627
HGNC 11152
MIM 603521
UniProt P09661  
 SNRPA1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for SNRPA1
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    protein binding GO:0005515 IPI
Biological Process
    RNA splicing GO:0008380 TAS
    gene expression GO:0010467 TAS
    mRNA splicing, via spliceosome GO:0000398 TAS
Subcellular Localization
    U2 snRNP GO:0005686 TAS
    small nuclear ribonucleoprotein complex GO:0030532 TAS
    spliceosomal complex GO:0005681 IDA
    nucleoplasm GO:0005654 TAS
    catalytic step 2 spliceosome GO:0071013 IDA
 Experiment description of studies that identified SNRPA1 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SNRPA1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SNRPB2 6629
Co-crystal Structure Homo sapiens
2 TCF1  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SNRPA1 is involved
PathwayEvidenceSource
mRNA Splicing - Major Pathway TAS Reactome





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