Gene description for PRKRIP1
Gene name PRKR interacting protein 1 (IL11 inducible)
Gene symbol PRKRIP1
Other names/aliases C114
KRBOX3
Species Homo sapiens
 Database cross references - PRKRIP1
ExoCarta ExoCarta_79706
Entrez Gene 79706
HGNC 21894
UniProt Q9H875  
 PRKRIP1 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for PRKRIP1
Molecular Function
    protein binding GO:0005515 IPI
    double-stranded RNA binding GO:0003725 ISS
    protein kinase binding GO:0019901 ISS
    protein kinase inhibitor activity GO:0004860 ISS
Biological Process
    negative regulation of protein kinase activity GO:0006469 ISS
    renal system process GO:0003014 IDA
    negative regulation of phosphorylation GO:0042326 ISS
Subcellular Localization
    nucleolus GO:0005730 ISS
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified PRKRIP1 in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for PRKRIP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RNU11 26824
Affinity Capture-MS Homo sapiens
2 MAGEA11  
Two-hybrid Homo sapiens
3 EIF2AK2 5610
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which PRKRIP1 is involved
No pathways found





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