Gene description for Elavl1
Gene name ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
Gene symbol Elavl1
Other names/aliases 2410055N02Rik
HUR
Hua
W91709
Species Mus musculus
 Database cross references - Elavl1
ExoCarta ExoCarta_15568
Entrez Gene 15568
UniProt P70372  
 Elavl1 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Elavl1
Molecular Function
    RNA binding GO:0003723 ISO
    AU-rich element binding GO:0017091 ISO
    double-stranded RNA binding GO:0003725 ISO
    nucleic acid binding GO:0003676 IEA
    poly(A) RNA binding GO:0044822 ISO
    protein kinase binding GO:0019901 ISO
    mRNA 3'-UTR AU-rich region binding GO:0035925 ISO
    nucleotide binding GO:0000166 IEA
    mRNA 3'-UTR binding GO:0003730 ISO
    protein binding GO:0005515 IPI
Biological Process
    mRNA stabilization GO:0048255 ISO
    positive regulation of translation GO:0045727 ISO
    regulation of stem cell maintenance GO:2000036 IMP
    3'-UTR-mediated mRNA stabilization GO:0070935 ISO
    regulation of translation GO:0006417 ISO
Subcellular Localization
    cytoplasm GO:0005737 ISO
    membrane GO:0016020 ISO
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Elavl1 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Elavl1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Elavl1 is involved
PathwayEvidenceSource
HuR stabilizes mRNA IEA Reactome





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