Gene description for ARHGAP9
Gene name Rho GTPase activating protein 9
Gene symbol ARHGAP9
Other names/aliases 10C
RGL1
Species Homo sapiens
 Database cross references - ARHGAP9
ExoCarta ExoCarta_64333
Entrez Gene 64333
HGNC 14130
MIM 610576
UniProt Q9BRR9  
 ARHGAP9 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for ARHGAP9
Molecular Function
    protein binding GO:0005515 IPI
    GTPase activator activity GO:0005096 IDA
    phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 IDA
Biological Process
    small GTPase mediated signal transduction GO:0007264 TAS
    positive regulation of GTPase activity GO:0043547 IEA
    regulation of small GTPase mediated signal transduction GO:0051056 TAS
Subcellular Localization
    cytosol GO:0005829 TAS
 Experiment description of studies that identified ARHGAP9 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ARHGAP9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SMAD9  
Affinity Capture-MS Homo sapiens
2 RBPMS  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ARHGAP9 is involved
PathwayEvidenceSource
Rho GTPase cycle TAS Reactome





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