Gene description for Mapk1
Gene name	mitogen activated protein kinase 1
Gene symbol	Mapk1
Other names/aliases	Erk2
Species	Rattus norvegicus
Database cross references - Mapk1
ExoCarta	ExoCarta_116590
Entrez Gene	116590
UniProt	P63086
Mapk1 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Mapk1

Molecular Function     protein kinase activity GO:0004672 ISO     kinase activity GO:0016301 TAS     protein binding GO:0005515 IPI     phosphatase binding GO:0019902 ISO     transcription factor binding GO:0008134 IPI     mitogen-activated protein kinase kinase kinase binding GO:0031435 IPI     protein kinase binding GO:0019901 IPI     MAP kinase activity GO:0004707 TAS     ATP binding GO:0005524 IDA     protein serine/threonine kinase activity GO:0004674 TAS     RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 ISO     phosphotyrosine binding GO:0001784 ISO Biological Process     B cell receptor signaling pathway GO:0050853 ISO     negative regulation of cell differentiation GO:0045596 ISO     positive regulation of cell proliferation GO:0008284 IEP     apoptotic process GO:0006915 IEA     response to estrogen GO:0043627 IDA     organ morphogenesis GO:0009887 ISO     T cell receptor signaling pathway GO:0050852 ISO     mammary gland epithelial cell proliferation GO:0033598 ISO     regulation of early endosome to late endosome transport GO:2000641 TAS     response to toxic substance GO:0009636 IDA     positive regulation of transcription, DNA-templated GO:0045893 IEP     peptidyl-serine phosphorylation GO:0018105 ISO     regulation of Golgi inheritance GO:0090170 TAS     regulation of cytoskeleton organization GO:0051493 TAS     caveolin-mediated endocytosis GO:0072584 TAS     cellular response to DNA damage stimulus GO:0006974 ISO     peptidyl-threonine phosphorylation GO:0018107 ISS     lung morphogenesis GO:0060425 ISO     positive regulation of translation GO:0045727 IMP     response to exogenous dsRNA GO:0043330 ISO     labyrinthine layer blood vessel development GO:0060716 ISO     ERK1 and ERK2 cascade GO:0070371 ISO     response to lipopolysaccharide GO:0032496 ISO     cellular response to granulocyte macrophage colony-stimulating factor stimulus GO:0097011 ISO     regulation of stress-activated MAPK cascade GO:0032872 TAS     positive regulation of cell migration GO:0030335 IEP     MAPK cascade GO:0000165 ISO     MAPK import into nucleus GO:0000189 IDA     lipopolysaccharide-mediated signaling pathway GO:0031663 ISO     intracellular signal transduction GO:0035556 TAS     cytosine metabolic process GO:0019858 ISO     positive regulation of peptidyl-threonine phosphorylation GO:0010800 ISO     cellular response to organic substance GO:0071310 IDA     trachea formation GO:0060440 ISO     signal transduction GO:0007165 IDA     regulation of protein stability GO:0031647 ISS     sensory perception of pain GO:0019233 IMP     long-term synaptic potentiation GO:0060291 ISO     ERBB signaling pathway GO:0038127 ISO     protein phosphorylation GO:0006468 TAS     response to epidermal growth factor GO:0070849 ISS Subcellular Localization     protein complex GO:0043234 IDA     extracellular exosome GO:0070062 ISO     cytosol GO:0005829 TAS     caveola GO:0005901 TAS     late endosome GO:0005770 TAS     dendrite cytoplasm GO:0032839 IDA     early endosome GO:0005769 TAS     perikaryon GO:0043204 IDA     cytoskeleton GO:0005856 TAS     microtubule cytoskeleton GO:0015630 ISO     mitotic spindle GO:0072686 ISS     nucleus GO:0005634 TAS     mitochondrion GO:0005739 TAS     nucleoplasm GO:0005654 TAS     intracellular GO:0005622 ISO     axon GO:0030424 IDA     microtubule organizing center GO:0005815 IEA     pseudopodium GO:0031143 ISO     cytoplasm GO:0005737 ISS     focal adhesion GO:0005925 TAS     Golgi apparatus GO:0005794 TAS