Gene description for Mapk3
Gene name	mitogen activated protein kinase 3
Gene symbol	Mapk3
Other names/aliases	ERK1 ERT2 Erk-1 Esrk1 MAPK1 MNK1 Prkm3 p44 p44erk1 p44mapk
Species	Rattus norvegicus
Database cross references - Mapk3
ExoCarta	ExoCarta_50689
Entrez Gene	50689
UniProt	P21708
Mapk3 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046

Gene ontology annotations for Mapk3

Molecular Function     protein serine/threonine kinase activity GO:0004674 IC     protein binding GO:0005515 IPI     phosphotyrosine binding GO:0001784 ISO     protein kinase activity GO:0004672 ISO     MAP kinase activity GO:0004707 ISO     scaffold protein binding GO:0097110 IPI     ATP binding GO:0005524 IDA     phosphatase binding GO:0019902 ISO Biological Process     sensory perception of pain GO:0019233 ISO     positive regulation of cyclase activity GO:0031281 ISO     positive regulation of translation GO:0045727 IMP     peptidyl-tyrosine autophosphorylation GO:0038083 ISO     positive regulation of transcription, DNA-templated GO:0045893 IEP     arachidonic acid metabolic process GO:0019369 IEP     phosphorylation GO:0016310 ISO     cellular response to DNA damage stimulus GO:0006974 ISO     regulation of stress-activated MAPK cascade GO:0032872 TAS     caveolin-mediated endocytosis GO:0072584 TAS     DNA damage induced protein phosphorylation GO:0006975 ISO     MAPK cascade GO:0000165 ISO     trachea formation GO:0060440 ISO     organ morphogenesis GO:0009887 ISO     cellular response to mechanical stimulus GO:0071260 ISO     transcription, DNA-templated GO:0006351 ISO     intracellular signal transduction GO:0035556 TAS     response to toxic substance GO:0009636 IDA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISO     positive regulation of protein phosphorylation GO:0001934 ISO     positive regulation of histone acetylation GO:0035066 ISO     ERK1 and ERK2 cascade GO:0070371 ISO     protein phosphorylation GO:0006468 TAS     lung morphogenesis GO:0060425 ISO     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO     apoptotic process GO:0006915 IEA     regulation of Golgi inheritance GO:0090170 TAS     regulation of early endosome to late endosome transport GO:2000641 TAS     MAPK import into nucleus GO:0000189 IDA     response to epidermal growth factor GO:0070849 ISS     BMP signaling pathway GO:0030509 ISO     interleukin-1-mediated signaling pathway GO:0070498 ISO     peptidyl-serine phosphorylation GO:0018105 IMP     response to lipopolysaccharide GO:0032496 ISO     protein complex assembly GO:0006461 IMP     negative regulation of apolipoprotein binding GO:2000657 ISO     regulation of sequence-specific DNA binding transcription factor activity GO:0051090 ISO     cartilage development GO:0051216 ISO     response to exogenous dsRNA GO:0043330 ISO     regulation of cytoskeleton organization GO:0051493 TAS     positive regulation of histone phosphorylation GO:0033129 ISO     lipopolysaccharide-mediated signaling pathway GO:0031663 ISO Subcellular Localization     cytoskeleton GO:0005856 TAS     intracellular GO:0005622 ISO     cytosol GO:0005829 TAS     extracellular exosome GO:0070062 ISO     late endosome GO:0005770 TAS     protein complex GO:0043234 IDA     nuclear envelope GO:0005635 ISO     cytoplasm GO:0005737 ISO     caveola GO:0005901 TAS     focal adhesion GO:0005925 TAS     Golgi apparatus GO:0005794 TAS     nucleoplasm GO:0005654 ISO     nucleus GO:0005634 TAS     early endosome GO:0005769 TAS     pseudopodium GO:0031143 ISO     microtubule cytoskeleton GO:0015630 ISO     mitochondrion GO:0005739 TAS