Gene description for ARHGAP35
Gene name	Rho GTPase activating protein 35
Gene symbol	ARHGAP35
Other names/aliases	GRF-1 GRLF1 P190-A P190A p190ARhoGAP p190RhoGAP
Species	Homo sapiens
Database cross references - ARHGAP35
ExoCarta	ExoCarta_2909
Entrez Gene	2909
HGNC	4591
MIM	605277
UniProt	Q9NRY4
ARHGAP35 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Endothelial cells	26027894
Neuroblastoma cells	25944692

Gene ontology annotations for ARHGAP35

Molecular Function     GTP binding GO:0005525 IEA     DNA binding GO:0003677 TAS     transcription corepressor activity GO:0003714 TAS     RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription GO:0001227 IDA     GTPase activator activity GO:0005096 TAS     RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 IDA Biological Process     negative regulation of vascular permeability GO:0043116 IEA     negative regulation of Rho protein signal transduction GO:0035024 IEA     small GTPase mediated signal transduction GO:0007264 TAS     camera-type eye development GO:0043010 IEA     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IDA     transcription, DNA-templated GO:0006351 IEA     axon guidance GO:0007411 TAS     neural tube closure GO:0001843 IEA     regulation of cell shape GO:0008360 IEA     positive regulation of neuron projection development GO:0010976 IEA     forebrain development GO:0030900 IEA     negative regulation of transcription, DNA-templated GO:0045892 IDA     regulation of small GTPase mediated signal transduction GO:0051056 TAS     positive regulation of GTPase activity GO:0043547 TAS Subcellular Localization     nucleus GO:0005634 IC     actin cytoskeleton GO:0015629 IEA     cytosol GO:0005829 TAS