Gene description for KCTD12
Gene name potassium channel tetramerization domain containing 12
Gene symbol KCTD12
Other names/aliases C13orf2
PFET1
PFETIN
Species Homo sapiens
 Database cross references - KCTD12
ExoCarta ExoCarta_115207
Entrez Gene 115207
HGNC 14678
MIM 610521
UniProt Q96CX2  
 KCTD12 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for KCTD12
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    protein homooligomerization GO:0051260 IEA
    regulation of G-protein coupled receptor protein signaling pathway GO:0008277 IEA
Subcellular Localization
    receptor complex GO:0043235 IEA
    presynaptic membrane GO:0042734 IEA
    extracellular exosome GO:0070062 IDA
    cell junction GO:0030054 IEA
    postsynaptic membrane GO:0045211 IEA
 Experiment description of studies that identified KCTD12 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for KCTD12
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RIPK2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which KCTD12 is involved
No pathways found





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