Gene description for PYCRL
Gene name pyrroline-5-carboxylate reductase-like
Gene symbol PYCRL
Other names/aliases -
Species Homo sapiens
 Database cross references - PYCRL
ExoCarta ExoCarta_65263
Entrez Gene 65263
HGNC 25846
UniProt Q53H96  
 PYCRL identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for PYCRL
Molecular Function
    protein binding GO:0005515 IPI
    pyrroline-5-carboxylate reductase activity GO:0004735 IEA
Biological Process
    L-proline biosynthetic process GO:0055129 IEA
    oxidation-reduction process GO:0055114 IEA
 Experiment description of studies that identified PYCRL in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PYCRL
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PYCRL is involved
No pathways found





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