Gene description for KCNG1
Gene name potassium channel, voltage gated modifier subfamily G, member 1
Gene symbol KCNG1
Other names/aliases K13
KCNG
KV6.1
kH2
Species Homo sapiens
 Database cross references - KCNG1
ExoCarta ExoCarta_3755
Entrez Gene 3755
HGNC 6248
MIM 603788
UniProt Q9UIX4  
 KCNG1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for KCNG1
Molecular Function
    potassium channel activity GO:0005267 NAS
    delayed rectifier potassium channel activity GO:0005251 ISS
Biological Process
    regulation of ion transmembrane transport GO:0034765 IEA
    synaptic transmission GO:0007268 TAS
    potassium ion transport GO:0006813 NAS
    protein homooligomerization GO:0051260 IEA
    potassium ion transmembrane transport GO:0071805 ISS
Subcellular Localization
    plasma membrane GO:0005886 TAS
    voltage-gated potassium channel complex GO:0008076 ISS
    integral component of membrane GO:0016021 IBA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified KCNG1 in exosomes
1
Experiment ID 237
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for KCNG1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KCNB1  
Invivo Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which KCNG1 is involved
PathwayEvidenceSource
Voltage gated Potassium channels TAS Reactome





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