Gene description for LBP
Gene name	lipopolysaccharide binding protein
Gene symbol	LBP
Other names/aliases	BPIFD2
Species	Homo sapiens
Database cross references - LBP
ExoCarta	ExoCarta_3929
Entrez Gene	3929
HGNC	6517
MIM	151990
UniProt	P18428
LBP identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113
Urine	19056867

Gene ontology annotations for LBP

Molecular Function     receptor binding GO:0005102 ISS     lipopolysaccharide binding GO:0001530 ISS     protein binding GO:0005515 IPI     lipoteichoic acid binding GO:0070891 IDA Biological Process     cellular response to lipoteichoic acid GO:0071223 IDA     positive regulation of interleukin-8 production GO:0032757 IDA     negative regulation of tumor necrosis factor production GO:0032720 IDA     leukocyte chemotaxis involved in inflammatory response GO:0002232 IEA     response to lipopolysaccharide GO:0032496 IDA     detection of molecule of bacterial origin GO:0032490 IDA     toll-like receptor 4 signaling pathway GO:0034142 TAS     toll-like receptor signaling pathway GO:0002224 TAS     lipopolysaccharide-mediated signaling pathway GO:0031663 IDA     cellular defense response GO:0006968 ISS     positive regulation of neutrophil chemotaxis GO:0090023 IEA     positive regulation of chemokine production GO:0032722 IEA     innate immune response GO:0045087 TAS     cellular response to lipopolysaccharide GO:0071222 IDA     defense response to Gram-positive bacterium GO:0050830 IDA     positive regulation of interleukin-6 production GO:0032755 IDA     acute-phase response GO:0006953 ISS     positive regulation of respiratory burst involved in inflammatory response GO:0060265 ISS     negative regulation of growth of symbiont in host GO:0044130 IEA     lipopolysaccharide transport GO:0015920 IDA     positive regulation of macrophage activation GO:0043032 IDA     positive regulation of toll-like receptor 4 signaling pathway GO:0034145 IDA     positive regulation of tumor necrosis factor biosynthetic process GO:0042535 IEA     positive regulation of tumor necrosis factor production GO:0032760 ISS     opsonization GO:0008228 ISS     defense response to Gram-negative bacterium GO:0050829 ISS     macrophage activation involved in immune response GO:0002281 ISS Subcellular Localization     cell surface GO:0009986 IDA     extracellular exosome GO:0070062 IDA     extracellular region GO:0005576 TAS     extracellular space GO:0005615 ISS