Gene description for CYTH2
Gene name
cytohesin 2
Gene symbol
CYTH2
Other names/aliases
ARNO CTS18 CTS18.1 PSCD2 PSCD2L SEC7L Sec7p-L Sec7p-like
Species
Homo sapiens
Database cross references - CYTH2
ExoCarta
ExoCarta_9266
Vesiclepedia
VP_9266
Entrez Gene
9266
HGNC
9502
MIM
602488
UniProt
Q99418
CYTH2 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Gene ontology annotations for CYTH2
Experiment description of studies that identified CYTH2 in exosomes
1
Experiment ID
211
MISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
EV Enriched markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
MISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
EV Enriched markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for CYTH2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
IPCEF1
26034
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
2
SFN
2810
Affinity Capture-MS
Homo sapiens
3
JM11
Two-hybrid
Homo sapiens
4
ARRB2
409
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
5
ARF3
Biochemical Activity
4932
6
TRIM23
373
Invitro
Homo sapiens
Invivo
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
7
ARRB1
408
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
8
ARF6
382
Affinity Capture-MS
Homo sapiens
Biochemical Activity
Homo sapiens
9
ARF1
375
Affinity Capture-MS
Homo sapiens
Biochemical Activity
Homo sapiens
View the network
image/svg+xml
Pathways in which CYTH2 is involved
No pathways found