Gene description for TMPO
Gene name thymopoietin
Gene symbol TMPO
Other names/aliases CMD1T
LAP2
LEMD4
PRO0868
TP
Species Homo sapiens
 Database cross references - TMPO
ExoCarta ExoCarta_7112
Vesiclepedia VP_7112
Entrez Gene 7112
HGNC 11875
MIM 188380
UniProt P42166   P42167  
 TMPO identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
 Gene ontology annotations for TMPO
Molecular Function
    DNA binding GO:0003677 IEA
    protein binding GO:0005515 IPI
    lamin binding GO:0005521 TAS
    cadherin binding GO:0045296 HDA
Subcellular Localization
    chromatin GO:0000785 IDA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 TAS
    nuclear envelope GO:0005635 IDA
    nuclear envelope GO:0005635 IEA
    nuclear inner membrane GO:0005637 IEA
    cytoplasm GO:0005737 IEA
    membrane GO:0016020 HDA
    nuclear membrane GO:0031965 IDA
 Experiment description of studies that identified TMPO in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
8
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
9
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
33
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
39
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
40
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
43
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
45
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
46
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
47
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
48
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
49
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
50
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
51
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
52
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
53
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
54
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
55
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
56
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
57
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for TMPO
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HIST1H4K 8362
Affinity Capture-MS Homo sapiens
2 GJD3  
Proximity Label-MS Homo sapiens
3 ISG15 9636
Affinity Capture-MS Homo sapiens
4 EIF2AK4 440275
Affinity Capture-MS Homo sapiens
5 DNAJC11 55735
Affinity Capture-MS Homo sapiens
6 KRTCAP2 200185
Affinity Capture-MS Homo sapiens
7 ATG9A 79065
Proximity Label-MS Homo sapiens
8 ARPC2 10109
Affinity Capture-MS Homo sapiens
9 TPM2 7169
Affinity Capture-MS Homo sapiens
10 CSNK1A1 1452
Affinity Capture-MS Homo sapiens
11 DDX17 10521
Affinity Capture-MS Homo sapiens
12 ACTC1 70
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
13 MTMR14 64419
Affinity Capture-MS Homo sapiens
14 KIF20A 10112
Affinity Capture-MS Homo sapiens
15 SLC25A1 6576
Affinity Capture-MS Homo sapiens
16 CSNK2A1 1457
Biochemical Activity Homo sapiens
17 HIST1H4H 8365
Affinity Capture-MS Homo sapiens
18 ACTB 60
Affinity Capture-MS Homo sapiens
19 GCN1L1 10985
Affinity Capture-MS Homo sapiens
20 SOX2  
Affinity Capture-MS Homo sapiens
21 AKAP8L  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
22 RPS2 6187
Affinity Capture-MS Homo sapiens
23 HDAC3 8841
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
24 HIST1H4E 8367
Affinity Capture-MS Homo sapiens
25 DPM1 8813
Affinity Capture-MS Homo sapiens
26 DARS 1615
Affinity Capture-MS Homo sapiens
27 GFPT1 2673
Affinity Capture-MS Homo sapiens
28 ACTR3 10096
Affinity Capture-MS Homo sapiens
29 AP2A1 160
Affinity Capture-MS Homo sapiens
30 STOM 2040
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
31 CALD1 800
Affinity Capture-MS Homo sapiens
32 HSPH1 10808
Affinity Capture-MS Homo sapiens
33 OIP5  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
34 RPS9 6203
Affinity Capture-MS Homo sapiens
35 EIF3E 3646
Affinity Capture-MS Homo sapiens
36 SLC25A46 91137
Proximity Label-MS Homo sapiens
37 HIST1H4I 8294
Affinity Capture-MS Homo sapiens
38 ZWINT  
Affinity Capture-MS Homo sapiens
39 MECP2 4204
Affinity Capture-MS Homo sapiens
40 NDUFS1 4719
Affinity Capture-MS Homo sapiens
41 RPS23 6228
Affinity Capture-MS Homo sapiens
42 RBM14 10432
Affinity Capture-MS Homo sapiens
43 KIF14 9928
Affinity Capture-MS Homo sapiens
44 EMC9  
Affinity Capture-MS Homo sapiens
45 UNK  
Affinity Capture-RNA Homo sapiens
46 CHMP4C 92421
Affinity Capture-MS Homo sapiens
47 FARSA 2193
Affinity Capture-MS Homo sapiens
48 TCP1 6950
Affinity Capture-MS Homo sapiens
49 MRE11A 4361
Co-fractionation Homo sapiens
50 PGAM5 192111
Affinity Capture-MS Homo sapiens
51 CLU 1191
Affinity Capture-MS Homo sapiens
52 MCAM 4162
Proximity Label-MS Homo sapiens
53 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
54 PABPC1 26986
Affinity Capture-MS Homo sapiens
55 CDH1 999
Proximity Label-MS Homo sapiens
56 PSMD2 5708
Affinity Capture-MS Homo sapiens
57 MYH9 4627
Affinity Capture-MS Homo sapiens
58 OGT 8473
Reconstituted Complex Homo sapiens
59 RAB7A 7879
Proximity Label-MS Homo sapiens
60 BANF1 8815
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
61 P4HB 5034
Affinity Capture-MS Homo sapiens
62 Mapk13  
Affinity Capture-MS Mus musculus
63 HECTD1 25831
Affinity Capture-MS Homo sapiens
64 SEC61B 10952
Proximity Label-MS Homo sapiens
65 HIST1H4C 8364
Affinity Capture-MS Homo sapiens
66 REEP5 7905
Proximity Label-MS Homo sapiens
67 ANLN 54443
Affinity Capture-MS Homo sapiens
68 TMPO 7112
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
69 HADHA 3030
Affinity Capture-MS Homo sapiens
70 C9orf78 51759
Affinity Capture-MS Homo sapiens
71 LMNB1 4001
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
72 SRSF4 6429
Affinity Capture-MS Homo sapiens
73 MYH14 79784
Affinity Capture-MS Homo sapiens
74 BCAP31 10134
Proximity Label-MS Homo sapiens
75 CUL3 8452
Affinity Capture-MS Homo sapiens
76 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
77 EPRS 2058
Affinity Capture-MS Homo sapiens
78 SDC2 6383
Affinity Capture-MS Homo sapiens
79 MYO1C 4641
Affinity Capture-MS Homo sapiens
80 HIST1H4B 8366
Affinity Capture-MS Homo sapiens
81 PCBP1 5093
Affinity Capture-MS Homo sapiens
82 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
83 MTTP 4547
Affinity Capture-MS Homo sapiens
84 DLST 1743
Affinity Capture-MS Homo sapiens
85 AP2A2 161
Affinity Capture-MS Homo sapiens
86 GANAB 23193
Affinity Capture-MS Homo sapiens
87 MYH10 4628
Affinity Capture-MS Homo sapiens
88 AP4S1 11154
Affinity Capture-MS Homo sapiens
89 TPM4 7171
Affinity Capture-MS Homo sapiens
90 PYHIN1  
Affinity Capture-MS Homo sapiens
91 PRKDC 5591
Affinity Capture-MS Homo sapiens
92 DDX46 9879
Affinity Capture-MS Homo sapiens
93 YBX1 4904
Affinity Capture-MS Homo sapiens
94 NUDT21 11051
Affinity Capture-MS Homo sapiens
95 FASN 2194
Affinity Capture-MS Homo sapiens
96 RUVBL2 10856
Affinity Capture-MS Homo sapiens
97 LRPPRC 10128
Affinity Capture-MS Homo sapiens
98 HIST1H2BC 8347
Affinity Capture-MS Homo sapiens
99 FYCO1 79443
Affinity Capture-MS Homo sapiens
100 UGDH 7358
Affinity Capture-MS Homo sapiens
101 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
102 PUF60 22827
Affinity Capture-MS Homo sapiens
103 RPS15A 6210
Affinity Capture-MS Homo sapiens
104 ATAD3A 55210
Affinity Capture-MS Homo sapiens
105 DDX3X 1654
Affinity Capture-MS Homo sapiens
106 HIST1H4L 8368
Affinity Capture-MS Homo sapiens
107 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
108 NCL 4691
Affinity Capture-MS Homo sapiens
109 HNRNPL 3191
Affinity Capture-MS Homo sapiens
110 SUPT6H 6830
Affinity Capture-MS Homo sapiens
111 SGMS2 166929
Affinity Capture-MS Homo sapiens
112 ATP5B 506
Affinity Capture-MS Homo sapiens
113 HIST1H4J 8363
Affinity Capture-MS Homo sapiens
114 ACO2 50
Affinity Capture-MS Homo sapiens
115 CUL7 9820
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 COLGALT1 79709
Affinity Capture-MS Homo sapiens
117 ANXA2 302
Affinity Capture-MS Homo sapiens
118 EXOSC8  
Affinity Capture-MS Homo sapiens
119 DERL1 79139
Proximity Label-MS Homo sapiens
120 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
121 MCM3 4172
Affinity Capture-MS Homo sapiens
122 KIF23 9493
Affinity Capture-MS Homo sapiens
123 SPRTN  
Affinity Capture-MS Homo sapiens
124 HSPA6 3310
Affinity Capture-MS Homo sapiens
125 METTL7A 25840
Proximity Label-MS Homo sapiens
126 LAMP3  
Proximity Label-MS Homo sapiens
127 RPS17 6218
Affinity Capture-MS Homo sapiens
128 TARDBP 23435
Affinity Capture-MS Homo sapiens
129 BTF3 689
Affinity Capture-MS Homo sapiens
130 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
131 SF3B1 23451
Affinity Capture-MS Homo sapiens
132 EIF4A1 1973
Affinity Capture-MS Homo sapiens
133 CAND1 55832
Affinity Capture-MS Homo sapiens
134 COPA 1314
Affinity Capture-MS Homo sapiens
135 RPS18 6222
Affinity Capture-MS Homo sapiens
136 B3GNT2 10678
Affinity Capture-MS Homo sapiens
137 NOLC1 9221
Affinity Capture-MS Homo sapiens
138 ARPC4 10093
Affinity Capture-MS Homo sapiens
139 PRC1 9055
Affinity Capture-MS Homo sapiens
140 SRRM2 23524
Affinity Capture-MS Homo sapiens
141 OBSL1 23363
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 HIST4H4 121504
Affinity Capture-MS Homo sapiens
143 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
144 PHB 5245
Affinity Capture-MS Homo sapiens
145 RAB5C 5878
Proximity Label-MS Homo sapiens
146 CTPS1 1503
Affinity Capture-MS Homo sapiens
147 USP7 7874
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
148 ICAM1 3383
Affinity Capture-MS Homo sapiens
149 CCT2 10576
Affinity Capture-MS Homo sapiens
150 TLR9  
Affinity Capture-MS Homo sapiens
151 ARPC1B 10095
Affinity Capture-MS Homo sapiens
152 SLC25A10 1468
Affinity Capture-MS Homo sapiens
153 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 RPL4 6124
Affinity Capture-MS Homo sapiens
155 WHSC1 7468
Proximity Label-MS Homo sapiens
156 PEG10 23089
Affinity Capture-MS Homo sapiens
157 SNRNP200 23020
Affinity Capture-MS Homo sapiens
158 HIST2H2BF 440689
Affinity Capture-MS Homo sapiens
159 MB21D2  
Co-fractionation Homo sapiens
160 TUBA1C 84790
Affinity Capture-MS Homo sapiens
161 APOB 338
Affinity Capture-MS Homo sapiens
162 UBTF 7343
Affinity Capture-MS Homo sapiens
163 IARS 3376
Affinity Capture-MS Homo sapiens
164 RAPGEF1 2889
Cross-Linking-MS (XL-MS) Homo sapiens
165 RAD21 5885
Affinity Capture-MS Homo sapiens
166 HNF1B  
Affinity Capture-MS Homo sapiens
167 CLN3 1201
Affinity Capture-MS Homo sapiens
168 RPN2 6185
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
169 CANX 821
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
170 SMARCAD1  
Affinity Capture-MS Homo sapiens
171 TP53BP1 7158
Affinity Capture-MS Homo sapiens
172 RAB5A 5868
Proximity Label-MS Homo sapiens
173 FAM50B  
Affinity Capture-MS Homo sapiens
174 JADE1  
Affinity Capture-MS Homo sapiens
175 SLC25A22  
Affinity Capture-MS Homo sapiens
176 PHIP 55023
Affinity Capture-MS Homo sapiens
177 HNRNPF 3185
Affinity Capture-MS Homo sapiens
178 RIPK4  
Affinity Capture-MS Homo sapiens
179 LARS 51520
Co-fractionation Homo sapiens
180 YWHAQ 10971
Affinity Capture-MS Homo sapiens
181 EFTUD2 9343
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
182 TPM1 7168
Affinity Capture-MS Homo sapiens
183 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
184 ATP2A1 487
Proximity Label-MS Homo sapiens
185 TMOD3 29766
Affinity Capture-MS Homo sapiens
186 HIST1H4F 8361
Affinity Capture-MS Homo sapiens
187 SNW1 22938
Affinity Capture-MS Homo sapiens
188 DDRGK1 65992
Affinity Capture-MS Homo sapiens
189 XRCC3  
Affinity Capture-MS Homo sapiens
190 LEMD3  
Affinity Capture-MS Homo sapiens
191 LMNA 4000
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
192 HUWE1 10075
Affinity Capture-MS Homo sapiens
193 PHGDH 26227
Affinity Capture-MS Homo sapiens
194 OST4  
Affinity Capture-MS Homo sapiens
195 RPL13 6137
Affinity Capture-MS Homo sapiens
196 SLC25A3 5250
Affinity Capture-MS Homo sapiens
197 EIF3F 8665
Affinity Capture-MS Homo sapiens
198 PARP1 142
Affinity Capture-MS Homo sapiens
199 HDGF 3068
Affinity Capture-MS Homo sapiens
200 PGRMC1 10857
Affinity Capture-MS Homo sapiens
201 FGB 2244
Affinity Capture-MS Homo sapiens
202 PTBP1 5725
Affinity Capture-MS Homo sapiens
203 SQSTM1 8878
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
204 RNF20 56254
Cross-Linking-MS (XL-MS) Homo sapiens
205 MAP2K1 5604
Affinity Capture-MS Homo sapiens
206 HNRNPK 3190
Affinity Capture-MS Homo sapiens
207 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 ERGIC2 51290
Proximity Label-MS Homo sapiens
209 BAG5 9529
Affinity Capture-MS Homo sapiens
210 GMPPA 29926
Co-fractionation Homo sapiens
211 YBX3 8531
Affinity Capture-MS Homo sapiens
212 RPL7A 6130
Affinity Capture-MS Homo sapiens
213 ATP1A1 476
Affinity Capture-MS Homo sapiens
214 PRDX1 5052
Affinity Capture-MS Homo sapiens
215 BRD1 23774
Affinity Capture-MS Homo sapiens
216 HSPG2 3339
Affinity Capture-MS Homo sapiens
217 GOLM1 51280
Two-hybrid Homo sapiens
218 CKAP4 10970
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
219 Cdc26  
Affinity Capture-MS Mus musculus
220 PRMT1 3276
Affinity Capture-MS Homo sapiens
221 SLC3A2 6520
Affinity Capture-MS Homo sapiens
222 MCM7 4176
Affinity Capture-MS Homo sapiens
223 HNRNPC 3183
Affinity Capture-MS Homo sapiens
224 IDH1 3417
Affinity Capture-MS Homo sapiens
225 DHCR24 1718
Affinity Capture-MS Homo sapiens
226 MARCKS 4082
Proximity Label-MS Homo sapiens
227 PFKP 5214
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
228 YWHAE 7531
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
229 HIST1H2BJ 8970
Affinity Capture-MS Homo sapiens
230 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
231 PTPN1 5770
Proximity Label-MS Homo sapiens
232 STX4 6810
Proximity Label-MS Homo sapiens
233 PCGF2 7703
Affinity Capture-Western Homo sapiens
234 ATG13 9776
Affinity Capture-MS Homo sapiens
235 KAT7  
Affinity Capture-MS Homo sapiens
236 AP2B1 163
Affinity Capture-MS Homo sapiens
237 RPL10A 4736
Affinity Capture-MS Homo sapiens
238 RUVBL1 8607
Affinity Capture-MS Homo sapiens
239 PRKCDBP 112464
Affinity Capture-MS Homo sapiens
240 VARS 7407
Affinity Capture-MS Homo sapiens
241 MLLT10  
Affinity Capture-MS Homo sapiens
242 EIF3B 8662
Affinity Capture-MS Homo sapiens
243 SSR1 6745
Proximity Label-MS Homo sapiens
244 PSMC2 5701
Affinity Capture-MS Homo sapiens
245 ATRX 546
Affinity Capture-MS Homo sapiens
246 CCDC47 57003
Affinity Capture-MS Homo sapiens
247 CSNK2B 1460
Affinity Capture-MS Homo sapiens
248 CLGN 1047
Affinity Capture-MS Homo sapiens
249 PABPC4 8761
Affinity Capture-MS Homo sapiens
250 HIST2H4A 8370
Affinity Capture-MS Homo sapiens
251 CHD1 1105
Affinity Capture-MS Homo sapiens
252 PXMP2  
Proximity Label-MS Homo sapiens
253 NF2 4771
Affinity Capture-MS Homo sapiens
254 RPL27 6155
Affinity Capture-MS Homo sapiens
255 DLD 1738
Affinity Capture-MS Homo sapiens
256 MYO18A 399687
Affinity Capture-MS Homo sapiens
257 FOXC1  
Affinity Capture-MS Homo sapiens
258 SAMM50 25813
Affinity Capture-MS Homo sapiens
259 RPL9 6133
Affinity Capture-MS Homo sapiens
260 PRPF8 10594
Affinity Capture-MS Homo sapiens
261 PARK2  
Affinity Capture-MS Homo sapiens
262 MARS 4141
Affinity Capture-MS Homo sapiens
263 RPL5 6125
Affinity Capture-MS Homo sapiens
264 PLOD2 5352
Co-fractionation Homo sapiens
265 CHMP4B 128866
Affinity Capture-MS Homo sapiens
266 RPA2 6118
Affinity Capture-MS Homo sapiens
267 IGHG1 3500
Affinity Capture-MS Homo sapiens
268 CIRBP 1153
Co-fractionation Homo sapiens
269 IGHG4 3503
Affinity Capture-MS Homo sapiens
270 U2AF2 11338
Affinity Capture-MS Homo sapiens
271 ARNT 405
Affinity Capture-MS Homo sapiens
272 DNAJA1 3301
Affinity Capture-MS Homo sapiens
273 RPA4  
Proximity Label-MS Homo sapiens
274 RPN1 6184
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
275 DHX9 1660
Affinity Capture-MS Homo sapiens
276 ENY2 56943
Affinity Capture-MS Homo sapiens
277 YAP1 10413
Affinity Capture-MS Homo sapiens
278 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
279 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
280 PCBP2 5094
Affinity Capture-MS Homo sapiens
281 RPL23A 6147
Affinity Capture-MS Homo sapiens
282 NTRK1 4914
Affinity Capture-MS Homo sapiens
283 ZBTB2 57621
Affinity Capture-MS Homo sapiens
284 SLC25A12 8604
Affinity Capture-MS Homo sapiens
285 HIST1H4D 8360
Affinity Capture-MS Homo sapiens
286 METTL14  
Affinity Capture-MS Homo sapiens
287 RPL17-C18orf32 100526842
Affinity Capture-MS Homo sapiens
288 ECT2 1894
Affinity Capture-MS Homo sapiens
289 AHNAK 79026
Affinity Capture-MS Homo sapiens
290 LMNB2 84823
Two-hybrid Homo sapiens
291 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
292 HSD3B7 80270
Proximity Label-MS Homo sapiens
293 HIST2H4B 554313
Affinity Capture-MS Homo sapiens
294 STIM1 6786
Proximity Label-MS Homo sapiens
295 CCT4 10575
Affinity Capture-MS Homo sapiens
296 FBXO6 26270
Affinity Capture-MS Homo sapiens
297 HNRNPUL1 11100
Affinity Capture-MS Homo sapiens
298 NCAPH 23397
Affinity Capture-MS Homo sapiens
299 MYO1D 4642
Affinity Capture-MS Homo sapiens
300 SEC16A 9919
Affinity Capture-MS Homo sapiens
301 RAB9A 9367
Proximity Label-MS Homo sapiens
302 RPL12 6136
Affinity Capture-MS Homo sapiens
303 HP1BP3 50809
Co-fractionation Homo sapiens
304 MATR3 9782
Affinity Capture-MS Homo sapiens
305 HYOU1 10525
Affinity Capture-MS Homo sapiens
306 HSPD1 3329
Affinity Capture-MS Homo sapiens
307 RNF185  
Affinity Capture-MS Homo sapiens
308 ILF3 3609
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
309 XRCC5 7520
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
310 TPM3 7170
Affinity Capture-MS Homo sapiens
311 IMMT 10989
Affinity Capture-MS Homo sapiens
312 TBX3 6926
Affinity Capture-MS Homo sapiens
313 AHSA1 10598
Affinity Capture-MS Homo sapiens
314 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
315 PHB2 11331
Affinity Capture-MS Homo sapiens
316 TMED10 10972
Affinity Capture-MS Homo sapiens
317 CCT8 10694
Affinity Capture-MS Homo sapiens
318 SMN1 6606
Affinity Capture-MS Homo sapiens
319 LIG3 3980
Affinity Capture-MS Homo sapiens
320 RPL6 6128
Affinity Capture-MS Homo sapiens
321 ERLIN1 10613
Affinity Capture-MS Homo sapiens
322 NLE1 54475
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
323 MCM5 4174
Affinity Capture-MS Homo sapiens
324 RPA1 6117
Affinity Capture-MS Homo sapiens
325 BST2 684
Affinity Capture-MS Homo sapiens
326 PDHA1 5160
Affinity Capture-MS Homo sapiens
327 HNRNPM 4670
Affinity Capture-MS Homo sapiens
328 ERLIN2 11160
Affinity Capture-MS Homo sapiens
329 Shoc2  
Affinity Capture-MS Mus musculus
330 ERGIC1 57222
Proximity Label-MS Homo sapiens
331 DDX58 23586
Affinity Capture-RNA Homo sapiens
332 MKI67  
Co-fractionation Homo sapiens
333 PDZD8 118987
Affinity Capture-MS Homo sapiens
334 UFL1 23376
Affinity Capture-MS Homo sapiens
335 RTCB 51493
Affinity Capture-MS Homo sapiens
336 FLNA 2316
Cross-Linking-MS (XL-MS) Homo sapiens
337 RPL8 6132
Affinity Capture-MS Homo sapiens
338 METTL3  
Affinity Capture-MS Homo sapiens
339 C14orf166 51637
Affinity Capture-MS Homo sapiens
340 VIM 7431
Affinity Capture-MS Homo sapiens
341 EIF3L 51386
Affinity Capture-MS Homo sapiens
342 UBE2H 7328
Affinity Capture-MS Homo sapiens
343 SLFN11 91607
Affinity Capture-MS Homo sapiens
344 ACTR2 10097
Affinity Capture-MS Homo sapiens
345 HSD17B11 51170
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
346 FMNL1 752
Affinity Capture-MS Homo sapiens
347 CCT3 7203
Affinity Capture-MS Homo sapiens
348 QARS 5859
Affinity Capture-MS Homo sapiens
349 SCARNA22  
Affinity Capture-RNA Homo sapiens
350 PAXIP1  
Affinity Capture-MS Homo sapiens
351 RPS3A 6189
Affinity Capture-MS Homo sapiens
352 VAPA 9218
Affinity Capture-MS Homo sapiens
353 RPS4X 6191
Affinity Capture-MS Homo sapiens
354 RPL30 6156
Affinity Capture-MS Homo sapiens
355 SUB1 10923
Affinity Capture-MS Homo sapiens
356 RPL10 6134
Affinity Capture-MS Homo sapiens
357 LAMP2 3920
Proximity Label-MS Homo sapiens
358 DNAJC25 548645
Proximity Label-MS Homo sapiens
359 CFL1 1072
Affinity Capture-MS Homo sapiens
360 SNRPD2 6633
Affinity Capture-MS Homo sapiens
361 HSPA5 3309
Affinity Capture-MS Homo sapiens
362 ILF2 3608
Affinity Capture-MS Homo sapiens
363 KIAA1429 25962
Affinity Capture-MS Homo sapiens
364 RPS11 6205
Affinity Capture-MS Homo sapiens
365 RPS6KA3 6197
Affinity Capture-MS Homo sapiens
366 B3GAT1  
Proximity Label-MS Homo sapiens
367 VIL1 7429
Affinity Capture-MS Homo sapiens
368 PC 5091
Affinity Capture-MS Homo sapiens
369 ATXN2L 11273
Affinity Capture-MS Homo sapiens
370 HIRIP3  
Affinity Capture-MS Homo sapiens
371 FBXW7  
Affinity Capture-MS Homo sapiens
372 RPL24 6152
Affinity Capture-MS Homo sapiens
373 Gmcl1  
Reconstituted Complex Mus musculus
374 FBXW8 26259
Affinity Capture-MS Homo sapiens
375 DDOST 1650
Affinity Capture-MS Homo sapiens
376 ABCE1 6059
Affinity Capture-MS Homo sapiens
377 CHMP1B 57132
Co-fractionation Homo sapiens
378 SERPINH1 871
Affinity Capture-MS Homo sapiens
379 MYO1B 4430
Affinity Capture-MS Homo sapiens
380 EED  
Affinity Capture-MS Homo sapiens
381 NUSAP1 51203
Affinity Capture-MS Homo sapiens
382 ATP6V0D1 9114
Affinity Capture-MS Homo sapiens
383 MYCN  
Affinity Capture-MS Homo sapiens
384 FAF2 23197
Affinity Capture-MS Homo sapiens
385 FAM20C 56975
Affinity Capture-MS Homo sapiens
386 TMEM63B 55362
Affinity Capture-MS Homo sapiens
387 GARS 2617
Affinity Capture-MS Homo sapiens
388 EDC4 23644
Affinity Capture-MS Homo sapiens
389 LRRC59 55379
Proximity Label-MS Homo sapiens
390 PPP1CA 5499
Affinity Capture-MS Homo sapiens
391 PPIB 5479
Affinity Capture-MS Homo sapiens
392 EMD 2010
Proximity Label-MS Homo sapiens
393 RB1CC1 9821
Affinity Capture-MS Homo sapiens
394 CCAR2 57805
Affinity Capture-MS Homo sapiens
395 HMGN2 3151
Co-fractionation Homo sapiens
396 CCT5 22948
Affinity Capture-MS Homo sapiens
397 SRSF6 6431
Affinity Capture-MS Homo sapiens
398 LRRFIP2 9209
Affinity Capture-MS Homo sapiens
399 VCP 7415
Affinity Capture-MS Homo sapiens
400 DDX5 1655
Affinity Capture-MS Homo sapiens
401 SUMO2 6613
Reconstituted Complex Homo sapiens
402 SRF  
Affinity Capture-MS Homo sapiens
403 CRY2  
Affinity Capture-MS Homo sapiens
404 Mad2l2  
Affinity Capture-MS Mus musculus
405 DDX1 1653
Affinity Capture-MS Homo sapiens
406 ELOVL5 60481
Proximity Label-MS Homo sapiens
407 CAPZB 832
Affinity Capture-MS Homo sapiens
408 CEBPA  
Protein-peptide Homo sapiens
409 EYA1  
Affinity Capture-MS Homo sapiens
410 DNAJB11 51726
Affinity Capture-MS Homo sapiens
411 MESDC2 23184
Co-fractionation Homo sapiens
412 ARRB1 408
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
413 SEC63 11231
Proximity Label-MS Homo sapiens
414 RPLP2 6181
Affinity Capture-MS Homo sapiens
415 FANCD2  
Affinity Capture-MS Homo sapiens
416 ASS1 445
Affinity Capture-MS Homo sapiens
417 KLHL6  
Two-hybrid Homo sapiens
418 OTUD1 220213
Affinity Capture-MS Homo sapiens
419 EIF4G1 1981
Affinity Capture-MS Homo sapiens
420 RPL35 11224
Affinity Capture-MS Homo sapiens
421 LAMP1 3916
Proximity Label-MS Homo sapiens
422 SRSF1 6426
Affinity Capture-MS Homo sapiens
423 DAD1 1603
Affinity Capture-MS Homo sapiens
424 RPL3 6122
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
425 MAB21L2  
Affinity Capture-MS Homo sapiens
426 RNF138  
Affinity Capture-MS Homo sapiens
427 ARF6 382
Proximity Label-MS Homo sapiens
428 RPL7 6129
Affinity Capture-MS Homo sapiens
429 MAPK6  
Affinity Capture-MS Homo sapiens
430 MYL6B 140465
Affinity Capture-MS Homo sapiens
431 ACSL3 2181
Affinity Capture-MS Homo sapiens
432 MYO6 4646
Affinity Capture-MS Homo sapiens
433 TXNL1 9352
Affinity Capture-MS Homo sapiens
434 SF3B3 23450
Affinity Capture-MS Homo sapiens
435 CLTC 1213
Affinity Capture-MS Homo sapiens
436 EIF4A2 1974
Affinity Capture-MS Homo sapiens
437 HNRNPU 3192
Affinity Capture-MS Homo sapiens
438 BRD3 8019
Affinity Capture-MS Homo sapiens
439 SH3KBP1 30011
Co-fractionation Homo sapiens
440 CCDC8  
Affinity Capture-MS Homo sapiens
441 Cbx1  
Affinity Capture-MS Mus musculus
442 DHX15 1665
Affinity Capture-MS Homo sapiens
443 ARRB2 409
Affinity Capture-MS Homo sapiens
444 GLUD1 2746
Affinity Capture-MS Homo sapiens
445 SLC25A11 8402
Affinity Capture-MS Homo sapiens
446 SPTAN1 6709
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
447 RRBP1 6238
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
448 PAPOLA 10914
Co-fractionation Homo sapiens
449 SRRM1 10250
Affinity Capture-MS Homo sapiens
450 TUBG1 7283
Affinity Capture-MS Homo sapiens
451 LGALS3 3958
Affinity Capture-MS Homo sapiens
452 SMURF1 57154
Affinity Capture-MS Homo sapiens
453 RPS15 6209
Affinity Capture-MS Homo sapiens
454 EIF4A3 9775
Affinity Capture-MS Homo sapiens
455 ATP2A2 488
Affinity Capture-MS Homo sapiens
456 RB1 5925
Affinity Capture-Western Homo sapiens
457 FADS2 9415
Affinity Capture-MS Homo sapiens
458 SEC62 7095
Proximity Label-MS Homo sapiens
459 CAD 790
Affinity Capture-MS Homo sapiens
460 AIRE  
Affinity Capture-MS Homo sapiens
461 SRSF7 6432
Affinity Capture-MS Homo sapiens
462 RPS8 6202
Affinity Capture-MS Homo sapiens
463 RARS 5917
Affinity Capture-MS Homo sapiens
464 C9orf72  
Affinity Capture-MS Homo sapiens
465 CDC5L 988
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TMPO is involved
No pathways found





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