Gene description for SLC25A11
Gene name solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
Gene symbol SLC25A11
Other names/aliases OGC
SLC20A4
Species Homo sapiens
 Database cross references - SLC25A11
ExoCarta ExoCarta_8402
Entrez Gene 8402
HGNC 10981
MIM 604165
UniProt Q02978  
 SLC25A11 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for SLC25A11
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    oxoglutarate:malate antiporter activity GO:0015367 TAS
Biological Process
    gluconeogenesis GO:0006094 TAS
    carbohydrate metabolic process GO:0005975 TAS
    transport GO:0006810 TAS
    alpha-ketoglutarate transport GO:0015742 TAS
    glucose metabolic process GO:0006006 TAS
    small molecule metabolic process GO:0044281 TAS
Subcellular Localization
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrion GO:0005739 IDA
    integral component of plasma membrane GO:0005887 TAS
    nucleus GO:0005634 IDA
 Experiment description of studies that identified SLC25A11 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SLC25A11
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 COPA 1314
Two-hybrid Homo sapiens
2 SLC25A11 8402
Invitro Homo sapiens
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
Invitro Homo sapiens
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SLC25A11 is involved
PathwayEvidenceSource
Gluconeogenesis TAS Reactome





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