Gene description for ASB15
Gene name ankyrin repeat and SOCS box containing 15
Gene symbol ASB15
Other names/aliases -
Species Homo sapiens
 Database cross references - ASB15
ExoCarta ExoCarta_142685
Vesiclepedia VP_142685
Entrez Gene 142685
HGNC 19767
UniProt Q8WXK1  
 ASB15 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for ASB15
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    protein ubiquitination GO:0016567 IEA
    intracellular signal transduction GO:0035556 IEA
Subcellular Localization
    cytosol GO:0005829 TAS
 Experiment description of studies that identified ASB15 in exosomes
1
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for ASB15
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 AGL 178
Affinity Capture-MS Homo sapiens
2 PRR35  
Two-hybrid Homo sapiens
3 MGC50722  
Two-hybrid Homo sapiens
4 IPO5 3843
Affinity Capture-MS Homo sapiens
5 TCEB1 6921
Affinity Capture-MS Homo sapiens
6 ACLY 47
Affinity Capture-MS Homo sapiens
7 WDR77 79084
Affinity Capture-MS Homo sapiens
8 SVIL 6840
Affinity Capture-MS Homo sapiens
9 GPI 2821
Affinity Capture-MS Homo sapiens
10 DLD 1738
Affinity Capture-MS Homo sapiens
11 CUL5 8065
Affinity Capture-MS Homo sapiens
12 PRPF8 10594
Affinity Capture-MS Homo sapiens
13 USP9X 8239
Affinity Capture-MS Homo sapiens
14 CCDC13 152206
Two-hybrid Homo sapiens
15 FTH1 2495
Affinity Capture-MS Homo sapiens
16 MIF 4282
Affinity Capture-MS Homo sapiens
17 DHRS2 10202
Affinity Capture-MS Homo sapiens
18 WDR61 80349
Affinity Capture-MS Homo sapiens
19 GEM  
Two-hybrid Homo sapiens
20 GAPDH 2597
Affinity Capture-MS Homo sapiens
21 KRT75 9119
Two-hybrid Homo sapiens
22 KANK2 25959
Two-hybrid Homo sapiens
23 GPSM3  
Two-hybrid Homo sapiens
24 TCEB2 6923
Affinity Capture-MS Homo sapiens
25 ZNF587  
Two-hybrid Homo sapiens
26 USHBP1  
Two-hybrid Homo sapiens
27 LMO1  
Two-hybrid Homo sapiens
28 VIM 7431
Affinity Capture-MS Homo sapiens
29 PRPF31 26121
Two-hybrid Homo sapiens
30 RPS16 6217
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here