Gene description for ASB15
Gene name ankyrin repeat and SOCS box containing 15
Gene symbol ASB15
Other names/aliases -
Species Homo sapiens
 Database cross references - ASB15
ExoCarta ExoCarta_142685
Entrez Gene 142685
HGNC 19767
UniProt Q8WXK1  
 ASB15 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for ASB15
Biological Process
    intracellular signal transduction GO:0035556 IEA
    protein ubiquitination GO:0016567 IEA
Subcellular Localization
    intracellular GO:0005622 IEA
 Experiment description of studies that identified ASB15 in exosomes
1
Experiment ID 224
ISEV standards
✔
EM|AFM
EV Biophysical techniques
✔
Alix|TSG101
EV Cytosolic markers
✔
CD63|CD81
EV Membrane markers
✔
GOLGA2
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for ASB15
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ASB15 is involved
PathwayEvidenceSource
Antigen processing: Ubiquitination & Proteasome degradation TAS Reactome





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