Gene description for CCDC13
Gene name coiled-coil domain containing 13
Gene symbol CCDC13
Other names/aliases -
Species Homo sapiens
 Database cross references - CCDC13
ExoCarta ExoCarta_152206
Vesiclepedia VP_152206
Entrez Gene 152206
HGNC 26358
UniProt Q8IYE1  
 CCDC13 identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for CCDC13
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    DNA damage response GO:0006974 IMP
    cytoplasmic microtubule organization GO:0031122 IBA
    cytoplasmic microtubule organization GO:0031122 IMP
    non-motile cilium assembly GO:1905515 IBA
    non-motile cilium assembly GO:1905515 IDA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    centrosome GO:0005813 IDA
    cytosol GO:0005829 IDA
    centriolar satellite GO:0034451 IBA
    centriolar satellite GO:0034451 IDA
    cell projection GO:0042995 IEA
 Experiment description of studies that identified CCDC13 in exosomes
1
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for CCDC13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPSA 3921
Two-hybrid Homo sapiens
2 TSGA10IP  
Two-hybrid Homo sapiens
3 DISC1 27185
Two-hybrid Homo sapiens
4 ENKD1  
Two-hybrid Homo sapiens
5 TP53BP2  
Two-hybrid Homo sapiens
6 EFHC2  
Two-hybrid Homo sapiens
7 MCRS1  
Two-hybrid Homo sapiens
8 ZBTB22  
Two-hybrid Homo sapiens
9 ASB15 142685
Two-hybrid Homo sapiens
10 HOMEZ  
Two-hybrid Homo sapiens
11 CCHCR1  
Two-hybrid Homo sapiens
12 VPS52 6293
Two-hybrid Homo sapiens
13 CCDC120  
Two-hybrid Homo sapiens
14 CARD9 64170
Two-hybrid Homo sapiens
15 EHHADH 1962
Two-hybrid Homo sapiens
16 KRT34  
Two-hybrid Homo sapiens
17 TXLNB  
Two-hybrid Homo sapiens
18 FCHO1  
Two-hybrid Homo sapiens
19 TCL1A  
Two-hybrid Homo sapiens
20 FAM161B  
Two-hybrid Homo sapiens
21 USP54 159195
Two-hybrid Homo sapiens
22 FAM90A1  
Two-hybrid Homo sapiens
23 HAP1  
Two-hybrid Homo sapiens
24 KIAA1328  
Two-hybrid Homo sapiens
25 OPTN 10133
Two-hybrid Homo sapiens
26 ZNF670  
Two-hybrid Homo sapiens
27 GOLGA2 2801
Two-hybrid Homo sapiens
28 FAM221B  
Two-hybrid Homo sapiens
29 PRDM16 63976
Two-hybrid Homo sapiens
30 NEFL 4747
Two-hybrid Homo sapiens
31 TRIM23 373
Two-hybrid Homo sapiens
32 FAM161A  
Two-hybrid Homo sapiens
33 TCHP  
Two-hybrid Homo sapiens
34 CDR2  
Two-hybrid Homo sapiens
35 MEOX2  
Two-hybrid Homo sapiens
36 CCDC136  
Two-hybrid Homo sapiens
37 HSF2BP  
Two-hybrid Homo sapiens
38 TRAF3 7187
Two-hybrid Homo sapiens
39 ZGPAT  
Two-hybrid Homo sapiens
40 MYF5  
Two-hybrid Homo sapiens
41 ZBTB43  
Two-hybrid Homo sapiens
42 ZBED1  
Two-hybrid Homo sapiens
43 CCND3  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which CCDC13 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here