Gene description for NEFL
Gene name	neurofilament, light polypeptide
Gene symbol	NEFL
Other names/aliases	CMT1F CMT2E NF-L NF68 NFL PPP1R110
Species	Homo sapiens
Database cross references - NEFL
ExoCarta	ExoCarta_4747
Vesiclepedia	VP_4747
Entrez Gene	4747
HGNC	7739
MIM	162280
UniProt	P07196
NEFL identified in exosomes derived from the following tissue/cell type
Liver cancer cells	25265333

Gene ontology annotations for NEFL

Molecular Function     protein binding GO:0005515 IPI     protein binding, bridging GO:0030674 ISS     phospholipase binding GO:0043274 IEA     protein C-terminus binding GO:0008022 IPI     protein domain specific binding GO:0019904 IEA     structural constituent of cytoskeleton GO:0005200 IDA     identical protein binding GO:0042802 IPI Biological Process     axon transport of mitochondrion GO:0019896 IMP     intermediate filament organization GO:0045109 IMP     anterograde axon cargo transport GO:0008089 IMP     neuron projection morphogenesis GO:0048812 IEA     regulation of axon diameter GO:0031133 IEA     positive regulation of axonogenesis GO:0050772 IEA     neuromuscular process controlling balance GO:0050885 IEA     locomotion GO:0040011 IEA     synaptic transmission GO:0007268 TAS     retrograde axon cargo transport GO:0008090 IMP     microtubule cytoskeleton organization GO:0000226 IEA     response to corticosterone GO:0051412 IEA     neurofilament bundle assembly GO:0033693 IMP     peripheral nervous system axon regeneration GO:0014012 IEA     response to toxic substance GO:0009636 IEA     negative regulation of neuron apoptotic process GO:0043524 IEA     response to peptide hormone GO:0043434 IEA     protein polymerization GO:0051258 IEA Subcellular Localization     cytosol GO:0005829 TAS     cytoplasm GO:0005737 ISS     TSC1-TSC2 complex GO:0033596 IDA     growth cone GO:0030426 IEA     neurofilament GO:0005883 IDA     axon GO:0030424 IDA