Gene description for RSPRY1
Gene name ring finger and SPRY domain containing 1
Gene symbol RSPRY1
Other names/aliases -
Species Homo sapiens
 Database cross references - RSPRY1
ExoCarta ExoCarta_89970
Entrez Gene 89970
HGNC 29420
UniProt Q96DX4  
 RSPRY1 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for RSPRY1
Molecular Function
    zinc ion binding GO:0008270 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified RSPRY1 in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for RSPRY1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RSPRY1 is involved
No pathways found





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