Gene description for ADAMTSL1
Gene name ADAMTS-like 1
Gene symbol ADAMTSL1
Other names/aliases ADAMTSL-1
ADAMTSR1
C9orf94
PUNCTIN
Species Homo sapiens
 Database cross references - ADAMTSL1
ExoCarta ExoCarta_92949
Vesiclepedia VP_92949
Entrez Gene 92949
HGNC 14632
MIM 609198
UniProt Q8N6G6  
 ADAMTSL1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for ADAMTSL1
Molecular Function
    hydrolase activity GO:0016787 IEA
Biological Process
    extracellular matrix organization GO:0030198 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
    endoplasmic reticulum lumen GO:0005788 TAS
 Experiment description of studies that identified ADAMTSL1 in exosomes
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ADAMTSL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPA2 6118
Proximity Label-MS Homo sapiens
2 DDRGK1 65992
Affinity Capture-MS Homo sapiens
3 RSPRY1 89970
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 FBN2 2201
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 GRN 2896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 CUL3 8452
Affinity Capture-MS Homo sapiens
7 ACOX1 51
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 FHL2 2274
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 C2orf44  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 B3GALTL 145173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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