Gene description for AGK
Gene name acylglycerol kinase
Gene symbol AGK
Other names/aliases CATC5
CTRCT38
MTDPS10
MULK
Species Homo sapiens
 Database cross references - AGK
ExoCarta ExoCarta_55750
Entrez Gene 55750
HGNC 21869
MIM 610345
UniProt Q53H12  
 AGK identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for AGK
Molecular Function
    ATP binding GO:0005524 IEA
    diacylglycerol kinase activity GO:0004143 IEA
    acylglycerol kinase activity GO:0047620 IEA
    ceramide kinase activity GO:0001729 IEA
Biological Process
    glycerolipid metabolic process GO:0046486 IEA
    ceramide biosynthetic process GO:0046513 IEA
    lipid phosphorylation GO:0046834 IEA
Subcellular Localization
    intracellular membrane-bounded organelle GO:0043231 IDA
    mitochondrial membrane GO:0031966 IEA
    mitochondrion GO:0005739 IDA
 Experiment description of studies that identified AGK in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for AGK
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which AGK is involved
No pathways found





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