Gene description for FGD4
Gene name	FYVE, RhoGEF and PH domain containing 4
Gene symbol	FGD4
Other names/aliases	CMT4H FRABP ZFYVE6
Species	Homo sapiens
Database cross references - FGD4
ExoCarta	ExoCarta_121512
Entrez Gene	121512
HGNC	19125
MIM	611104
UniProt	Q96M96
FGD4 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for FGD4

Molecular Function     metal ion binding GO:0046872 IEA     small GTPase binding GO:0031267 ISS     Rho guanyl-nucleotide exchange factor activity GO:0005089 IEA     actin binding GO:0003779 IEA     guanyl-nucleotide exchange factor activity GO:0005085 ISS Biological Process     regulation of small GTPase mediated signal transduction GO:0051056 TAS     cytoskeleton organization GO:0007010 ISS     filopodium assembly GO:0046847 ISS     small GTPase mediated signal transduction GO:0007264 TAS     positive regulation of apoptotic process GO:0043065 TAS     regulation of GTPase activity GO:0043087 ISS     regulation of cell shape GO:0008360 ISS     positive regulation of GTPase activity GO:0043547 ISS     actin cytoskeleton organization GO:0030036 ISS     lamellipodium assembly GO:0030032 IEA     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     microspike assembly GO:0030035 IEA     apoptotic signaling pathway GO:0097190 TAS Subcellular Localization     cytoplasm GO:0005737 ISS     ruffle GO:0001726 ISS     filopodium GO:0030175 IEA     Golgi apparatus GO:0005794 ISS     lamellipodium GO:0030027 ISS     actin cytoskeleton GO:0015629 IDA     cytosol GO:0005829 TAS