Gene description for HSDL2
Gene name hydroxysteroid dehydrogenase like 2
Gene symbol HSDL2
Other names/aliases C9orf99
SDR13C1
Species Homo sapiens
 Database cross references - HSDL2
ExoCarta ExoCarta_84263
Entrez Gene 84263
HGNC 18572
UniProt Q6YN16  
 HSDL2 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for HSDL2
Molecular Function
    oxidoreductase activity GO:0016491 IEA
    molecular_function GO:0003674 ND
Biological Process
    biological_process GO:0008150 ND
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    peroxisome GO:0005777 IDA
    membrane GO:0016020 IDA
    mitochondrion GO:0005739 IEA
 Experiment description of studies that identified HSDL2 in exosomes
1
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HSDL2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HSDL2 is involved
No pathways found





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