Gene description for MYEF2
Gene name myelin expression factor 2
Gene symbol MYEF2
Other names/aliases HsT18564
MEF-2
MST156
MSTP156
myEF-2
Species Homo sapiens
 Database cross references - MYEF2
ExoCarta ExoCarta_50804
Vesiclepedia VP_50804
Entrez Gene 50804
HGNC 17940
UniProt Q9P2K5  
 MYEF2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for MYEF2
Molecular Function
    DNA binding GO:0003677 IEA
    RNA binding GO:0003723 HDA
    mRNA binding GO:0003729 IBA
    protein binding GO:0005515 IPI
Biological Process
    myotube differentiation GO:0014902 IEP
    neuron differentiation GO:0030182 IEP
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified MYEF2 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MYEF2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATG16L1 55054
Affinity Capture-MS Homo sapiens
2 ATXN1 6310
Affinity Capture-Western Homo sapiens
3 FOXH1  
Affinity Capture-MS Homo sapiens
4 MECP2 4204
Affinity Capture-MS Homo sapiens
5 MAPK14 1432
Affinity Capture-Western Homo sapiens
6 OGT 8473
Reconstituted Complex Homo sapiens
7 MYCN  
Affinity Capture-MS Homo sapiens
8 PHIP 55023
Affinity Capture-MS Homo sapiens
9 SIRT6  
Affinity Capture-MS Homo sapiens
10 ATP6AP1 537
Affinity Capture-MS Homo sapiens
11 RPLP0 6175
Affinity Capture-MS Homo sapiens
12 LAMB3 3914
Affinity Capture-MS Homo sapiens
13 HDAC5 10014
Affinity Capture-Western Homo sapiens
14 ERLIN1 10613
Affinity Capture-MS Homo sapiens
15 RC3H2  
Affinity Capture-MS Homo sapiens
16 EXO1  
Affinity Capture-MS Homo sapiens
17 SIRT7  
Affinity Capture-MS Homo sapiens
18 NFKBID  
Two-hybrid Homo sapiens
19 COG8 84342
Two-hybrid Homo sapiens
20 RPA2 6118
Proximity Label-MS Homo sapiens
21 RPL37A 6168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 MEN1 4221
Affinity Capture-MS Homo sapiens
23 ADNP2  
Affinity Capture-MS Homo sapiens
24 CDK19 23097
Co-fractionation Homo sapiens
25 HNRNPM 4670
Affinity Capture-MS Homo sapiens
26 NR3C1 2908
Proximity Label-MS Homo sapiens
27 HNRNPD 3184
Affinity Capture-MS Homo sapiens
28 RPL14 9045
Affinity Capture-MS Homo sapiens
29 FOXI2  
Affinity Capture-MS Homo sapiens
30 HNRNPA1 3178
Proximity Label-MS Homo sapiens
31 TUB  
Affinity Capture-MS Homo sapiens
32 NUP35 129401
Proximity Label-MS Homo sapiens
33 TAF1  
Affinity Capture-MS Homo sapiens
34 RBM4B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 SOX2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 STOML2 30968
Affinity Capture-MS Homo sapiens
37 PRPF40B  
Affinity Capture-MS Homo sapiens
38 SFXN1 94081
Affinity Capture-MS Homo sapiens
39 GOLGA2 2801
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
40 USP36  
Affinity Capture-MS Homo sapiens
41 NKAP 79576
Affinity Capture-MS Homo sapiens
42 PRMT5 10419
Affinity Capture-MS Homo sapiens
43 GPATCH4 54865
Affinity Capture-MS Homo sapiens
44 PLEKHG4  
Two-hybrid Homo sapiens
45 SMARCA4 6597
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
46 COPB2 9276
Affinity Capture-MS Homo sapiens
47 TADA2A  
Affinity Capture-MS Homo sapiens
48 SP100 6672
Affinity Capture-MS Homo sapiens
49 IL17B 27190
Affinity Capture-MS Homo sapiens
50 RPA3 6119
Proximity Label-MS Homo sapiens
51 STX3 6809
Affinity Capture-MS Homo sapiens
52 ACTN4 81
Affinity Capture-MS Homo sapiens
53 NTRK1 4914
Affinity Capture-MS Homo sapiens
54 SSSCA1 10534
Affinity Capture-MS Homo sapiens
55 RPS6 6194
Affinity Capture-MS Homo sapiens
56 ERP29 10961
Co-fractionation Homo sapiens
57 BRD1 23774
Affinity Capture-MS Homo sapiens
58 RPL36 25873
Affinity Capture-MS Homo sapiens
59 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
60 CUL7 9820
Affinity Capture-MS Homo sapiens
61 DDRGK1 65992
Affinity Capture-MS Homo sapiens
62 RNF2  
Affinity Capture-MS Homo sapiens
63 BMI1  
Affinity Capture-MS Homo sapiens
64 LYAR 55646
Affinity Capture-MS Homo sapiens
65 OIP5  
Two-hybrid Homo sapiens
66 OBSL1 23363
Affinity Capture-MS Homo sapiens
67 KIDINS220 57498
Affinity Capture-MS Homo sapiens
68 MAGEB2 4113
Affinity Capture-MS Homo sapiens
69 PPARGC1A  
Affinity Capture-Western Homo sapiens
70 FLOT2 2319
Affinity Capture-MS Homo sapiens
71 NSUN4  
Affinity Capture-MS Homo sapiens
72 TRAF1 7185
Two-hybrid Homo sapiens
73 TEX11  
Two-hybrid Homo sapiens
74 PRKRA 8575
Affinity Capture-MS Homo sapiens
75 FLOT1 10211
Affinity Capture-MS Homo sapiens
76 EED  
Affinity Capture-MS Homo sapiens
77 PROSC 11212
Co-fractionation Homo sapiens
78 TRIM23 373
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which MYEF2 is involved
No pathways found





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