Gene description for SSFA2
Gene name sperm specific antigen 2
Gene symbol SSFA2
Other names/aliases CS-1
CS1
KRAP
SPAG13
Species Homo sapiens
 Database cross references - SSFA2
ExoCarta ExoCarta_6744
Entrez Gene 6744
HGNC 11319
MIM 118990
UniProt P28290  
 SSFA2 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for SSFA2
Molecular Function
    actin filament binding GO:0051015 IDA
    receptor binding GO:0005102 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    nucleoplasm GO:0005654 IDA
    plasma membrane GO:0005886 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified SSFA2 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for SSFA2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LUC7L2  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SSFA2 is involved
No pathways found





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