Experiment description of studies that identified MYPN in exosomes

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for MYPN

Protein Interactor ExoCarta ID Identification method PubMed Species 1 NEBL 10529 Two-hybrid Homo sapiens 2 TRIP6 7205 Affinity Capture-MS Homo sapiens 3 PALLD 23022 Affinity Capture-MS Homo sapiens 4 MTA2 9219 Co-fractionation Homo sapiens 5 SSFA2 6744 Affinity Capture-MS Homo sapiens 6 KIF14 9928 Affinity Capture-MS Homo sapiens 7 XPO1 7514 Affinity Capture-MS Homo sapiens 8 PHLPP1   Proximity Label-MS Homo sapiens 9 DHX8 1659 Co-fractionation Homo sapiens 10 CAPZA2 830 Affinity Capture-MS Homo sapiens 11 NEB 4703 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 12 ACTN3 89 Two-hybrid Homo sapiens 13 HOMER1   Affinity Capture-MS Homo sapiens 14 GTSE1 51512 Affinity Capture-MS Homo sapiens 15 Ppp6r1   Affinity Capture-MS Mus musculus 16 BAG6 7917 Affinity Capture-MS Homo sapiens 17 HOMER3 9454 Affinity Capture-MS Homo sapiens 18 HOMER2   Affinity Capture-MS Homo sapiens 19 ANKRD1 27063 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 20 DENND2D   Co-fractionation Homo sapiens 21 TTN 7273 Two-hybrid Homo sapiens 22 Mis12   Affinity Capture-MS Mus musculus 23 MCM2 4171 Affinity Capture-MS Homo sapiens 24 ACTN2 88 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 25 ANKRD23 200539 Two-hybrid Homo sapiens Two-hybrid Homo sapiens View the network

Pathways in which MYPN is involved

No pathways found