Gene description for NEBL
Gene name nebulette
Gene symbol NEBL
Other names/aliases LASP2
Species Homo sapiens
 Database cross references - NEBL
ExoCarta ExoCarta_10529
Entrez Gene 10529
HGNC 16932
MIM 605491
UniProt O76041  
 NEBL identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for NEBL
Molecular Function
    structural constituent of muscle GO:0008307 NAS
    protein binding GO:0005515 IPI
    cytoskeletal protein binding GO:0008092 IPI
    filamin binding GO:0031005 IPI
    actin filament binding GO:0051015 IDA
    tropomyosin binding GO:0005523 IPI
Biological Process
    cardiac muscle thin filament assembly GO:0071691 IMP
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    Z disc GO:0030018 IDA
    I band GO:0031674 NAS
    stress fiber GO:0001725 IDA
 Experiment description of studies that identified NEBL in exosomes
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for NEBL
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZYX 7791
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
2 MYPN 84665
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which NEBL is involved
No pathways found

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