Gene description for PDE5A
Gene name	phosphodiesterase 5A, cGMP-specific
Gene symbol	PDE5A
Other names/aliases	CGB-PDE CN5A PDE5
Species	Homo sapiens
Database cross references - PDE5A
ExoCarta	ExoCarta_8654
Entrez Gene	8654
HGNC	8784
MIM	603310
UniProt	O76074
PDE5A identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for PDE5A

Molecular Function     metal ion binding GO:0046872 IEA     cGMP binding GO:0030553 TAS     3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 IEA     3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 NAS Biological Process     positive regulation of oocyte development GO:0060282 IEA     relaxation of cardiac muscle GO:0055119 IEA     negative regulation of T cell proliferation GO:0042130 IEA     regulation of cGMP metabolic process GO:0030823 IEA     positive regulation of cardiac muscle hypertrophy GO:0010613 IEA     blood coagulation GO:0007596 TAS     cGMP catabolic process GO:0046069 IEA     signal transduction GO:0007165 IEA     positive regulation of MAP kinase activity GO:0043406 IEA     negative regulation of cardiac muscle contraction GO:0055118 IEA Subcellular Localization     cellular_component GO:0005575 ND     cytosol GO:0005829 TAS