Gene description for OXTR
Gene name	oxytocin receptor
Gene symbol	OXTR
Other names/aliases	OT-R
Species	Homo sapiens
Database cross references - OXTR
ExoCarta	ExoCarta_5021
Vesiclepedia	VP_5021
Entrez Gene	5021
HGNC	8529
MIM	167055
UniProt	P30559
OXTR identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for OXTR

Molecular Function     oxytocin receptor activity GO:0004990 IBA     vasopressin receptor activity GO:0005000 IBA     peptide hormone binding GO:0017046 IEA     ionotropic glutamate receptor binding GO:0035255 IEA Biological Process     suckling behavior GO:0001967 IEA     response to amphetamine GO:0001975 IEA     regulation of systemic arterial blood pressure by vasopressin GO:0001992 IBA     muscle contraction GO:0006936 TAS     cell surface receptor signaling pathway GO:0007166 TAS     G protein-coupled receptor signaling pathway GO:0007186 IBA     positive regulation of cytosolic calcium ion concentration GO:0007204 IEA     heart development GO:0007507 IEA     female pregnancy GO:0007565 IBA     lactation GO:0007595 TAS     memory GO:0007613 IEA     response to xenobiotic stimulus GO:0009410 IEA     positive regulation of norepinephrine secretion GO:0010701 IEA     telencephalon development GO:0021537 IEA     positive regulation of synaptic transmission, GABAergic GO:0032230 IEA     response to estradiol GO:0032355 IEA     response to progesterone GO:0032570 IEA     cellular response to hormone stimulus GO:0032870 IBA     response to anoxia GO:0034059 IEA     response to cytokine GO:0034097 IEA     social behavior GO:0035176 IEA     response to cocaine GO:0042220 IEA     maternal behavior GO:0042711 IEA     sperm ejaculation GO:0042713 IEA     eating behavior GO:0042755 IEA     response to peptide hormone GO:0043434 IEA     estrous cycle GO:0044849 IEA     positive regulation of blood pressure GO:0045777 IEA     positive regulation of vasoconstriction GO:0045907 IBA     digestive tract development GO:0048565 IEA     positive regulation of synapse assembly GO:0051965 IEA     positive regulation of synaptic transmission, glutamatergic GO:0051968 IEA     maternal process involved in parturition GO:0060137 IBA     positive regulation of penile erection GO:0060406 IEA     ERK1 and ERK2 cascade GO:0070371 IEA     positive regulation of uterine smooth muscle contraction GO:0070474 IEA     positive regulation of cold-induced thermogenesis GO:0120162 ISS Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 TAS     microvillus GO:0005902 IEA     adherens junction GO:0005912 IEA     apical plasma membrane GO:0016324 IEA