Gene description for RBP1
Gene name retinol binding protein 1, cellular
Gene symbol RBP1
Other names/aliases CRABP-I
CRBP
CRBP1
CRBPI
RBPC
Species Homo sapiens
 Database cross references - RBP1
ExoCarta ExoCarta_5947
Entrez Gene 5947
HGNC 9919
MIM 180260
UniProt P09455  
 RBP1 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for RBP1
Molecular Function
    transporter activity GO:0005215 IEA
    retinoid binding GO:0005501 TAS
    retinal binding GO:0016918 IEA
    retinol binding GO:0019841 IEA
Biological Process
    transport GO:0006810 IEA
    vitamin A metabolic process GO:0006776 TAS
    phototransduction, visible light GO:0007603 TAS
    retinoid metabolic process GO:0001523 TAS
Subcellular Localization
    cytosol GO:0005829 TAS
 Experiment description of studies that identified RBP1 in exosomes
1
Experiment ID 224
ISEV standards
✔
EM|AFM
EV Biophysical techniques
✔
Alix|TSG101
EV Cytosolic markers
✔
CD63|CD81
EV Membrane markers
✔
GOLGA2
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for RBP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LRP2 4036
Reconstituted Complex Homo sapiens
View the network image/svg+xml



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