Gene description for KIF9
Gene name kinesin family member 9
Gene symbol KIF9
Other names/aliases -
Species Homo sapiens
 Database cross references - KIF9
ExoCarta ExoCarta_64147
Vesiclepedia VP_64147
Entrez Gene 64147
HGNC 16666
MIM 607910
UniProt Q9HAQ2  
 KIF9 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
Urine 19056867    
 Gene ontology annotations for KIF9
Molecular Function
    microtubule motor activity GO:0003777 IBA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    microtubule binding GO:0008017 IBA
    ATP hydrolysis activity GO:0016887 IBA
    identical protein binding GO:0042802 IPI
Biological Process
    microtubule-based movement GO:0007018 IBA
    extracellular matrix disassembly GO:0022617 IMP
    regulation of podosome assembly GO:0071801 IMP
    regulation of flagellated sperm motility GO:1901317 ISS
    organelle disassembly GO:1903008 IMP
Subcellular Localization
    podosome GO:0002102 IDA
    cytoplasm GO:0005737 IBA
    kinesin complex GO:0005871 IBA
    microtubule GO:0005874 IBA
    microtubule GO:0005874 IDA
    vesicle GO:0031982 IDA
    sperm flagellum GO:0036126 ISS
 Experiment description of studies that identified KIF9 in sEVs
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for KIF9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZBTB8A  
Two-hybrid Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 CARD9 64170
Two-hybrid Homo sapiens
4 ROPN1  
Two-hybrid Homo sapiens
5 SMARCA2 6595
Cross-Linking-MS (XL-MS) Homo sapiens
6 LZTS2 84445
Two-hybrid Homo sapiens
7 RBM5  
Two-hybrid Homo sapiens
8 TRIM37  
Two-hybrid Homo sapiens
9 PRMT6  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
10 NEDD8-MDP1 100528064
Affinity Capture-MS Homo sapiens
11 EFHC2  
Two-hybrid Homo sapiens
12 XRCC6 2547
Cross-Linking-MS (XL-MS) Homo sapiens
13 JAKMIP2  
Two-hybrid Homo sapiens
14 FAM188A 80013
Affinity Capture-MS Homo sapiens
15 TP53 7157
Affinity Capture-MS Homo sapiens
16 KRTAP10-3  
Two-hybrid Homo sapiens
17 KRTAP10-9  
Two-hybrid Homo sapiens
18 IKZF1  
Two-hybrid Homo sapiens
19 TRIM27  
Two-hybrid Homo sapiens
20 SSX2IP  
Two-hybrid Homo sapiens
View the network image/svg+xml



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