Gene description for CSN3
Gene name casein kappa
Gene symbol CSN3
Other names/aliases CSN10
CSNK
KCA
Species Homo sapiens
 Database cross references - CSN3
ExoCarta ExoCarta_1448
Vesiclepedia VP_1448
Entrez Gene 1448
HGNC 2446
MIM 601695
UniProt P07498  
 CSN3 identified in exosomes derived from the following tissue/cell type
Breast milk 17641064    
 Gene ontology annotations for CSN3
Molecular Function
    molecular_function GO:0003674 ND
    protein binding GO:0005515 IPI
Biological Process
    transmembrane transport GO:0055085 TAS
    lactation GO:0007595 IDA
    protein stabilization GO:0050821 IDA
Subcellular Localization
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 IDA
 Experiment description of studies that identified CSN3 in exosomes
1
Experiment ID 48
MISEV standards
✔
EM|IEM
EV Biophysical techniques
✔
HSC70|CD63|CD86|MHCII
EV Enriched markers
✔
CANX
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17641064    
Organism Homo sapiens
Experiment description Exosomes with immune modulatory features are present in human breast milk.
Authors Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S
Journal name JIMMU
Publication year 2007
Sample Breast milk
Sample name Breast milk - Mature milk
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.10-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
FACS
 Protein-protein interactions for CSN3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CSNK2A2 1459
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
2 EIF3E 3646
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which CSN3 is involved
PathwayEvidenceSource
Miscellaneous transport and binding events TAS Reactome





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