Gene description for APOC2
Gene name	apolipoprotein C-II
Gene symbol	APOC2
Other names/aliases	APO-CII APOC-II
Species	Homo sapiens
Database cross references - APOC2
ExoCarta	ExoCarta_344
Entrez Gene	344
HGNC	609
MIM	608083
UniProt	P02655
APOC2 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells	25844599

Gene ontology annotations for APOC2

Molecular Function     phospholipase binding GO:0043274 IPI     lipid binding GO:0008289 IDA     phospholipase activator activity GO:0016004 IDA     lipoprotein lipase activator activity GO:0060230 IDA     protein homodimerization activity GO:0042803 IMP     lipase inhibitor activity GO:0055102 IDA Biological Process     negative regulation of catalytic activity GO:0043086 IDA     chylomicron remnant clearance GO:0034382 IDA     negative regulation of cholesterol transport GO:0032375 IMP     negative regulation of very-low-density lipoprotein particle clearance GO:0010916 IDA     positive regulation of phospholipid catabolic process GO:0060697 IDA     triglyceride-rich lipoprotein particle remodeling GO:0034370 TAS     positive regulation of fatty acid biosynthetic process GO:0045723 IDA     retinoid metabolic process GO:0001523 TAS     triglyceride homeostasis GO:0070328 IMP     reverse cholesterol transport GO:0043691 IC     chylomicron remodeling GO:0034371 IC     cholesterol efflux GO:0033344 IDA     phospholipid efflux GO:0033700 IDA     positive regulation of very-low-density lipoprotein particle remodeling GO:0010902 IC     cholesterol homeostasis GO:0042632 IC     high-density lipoprotein particle clearance GO:0034384 IMP     small molecule metabolic process GO:0044281 TAS     positive regulation of lipoprotein lipase activity GO:0051006 IDA     negative regulation of lipid metabolic process GO:0045833 IDA     positive regulation of phospholipase activity GO:0010518 IDA     positive regulation of triglyceride catabolic process GO:0010898 IDA     lipoprotein metabolic process GO:0042157 TAS     very-low-density lipoprotein particle remodeling GO:0034372 TAS     negative regulation of receptor-mediated endocytosis GO:0048261 IDA     phototransduction, visible light GO:0007603 TAS     lipid catabolic process GO:0016042 IEA Subcellular Localization     chylomicron GO:0042627 IDA     intermediate-density lipoprotein particle GO:0034363 IDA     extracellular space GO:0005615 IDA     early endosome GO:0005769 TAS     spherical high-density lipoprotein particle GO:0034366 IDA     extracellular exosome GO:0070062 IDA     very-low-density lipoprotein particle GO:0034361 IDA     extracellular region GO:0005576 TAS     low-density lipoprotein particle GO:0034362 IDA