Gene description for SNAP47
Gene name synaptosomal-associated protein, 47kDa
Gene symbol SNAP47
Other names/aliases C1orf142
HEL170
SNAP-47
SVAP1
Species Homo sapiens
 Database cross references - SNAP47
ExoCarta ExoCarta_116841
Vesiclepedia VP_116841
Entrez Gene 116841
HGNC 30669
UniProt Q5SQN1  
 SNAP47 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for SNAP47
Molecular Function
    SNAP receptor activity GO:0005484 IBA
    protein binding GO:0005515 IPI
    syntaxin binding GO:0019905 IBA
Biological Process
    exocytosis GO:0006887 IBA
    synaptic vesicle priming GO:0016082 IBA
    synaptic vesicle fusion to presynaptic active zone membrane GO:0031629 IBA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    endomembrane system GO:0012505 IEA
    BLOC-1 complex GO:0031083 IDA
    SNARE complex GO:0031201 IBA
    perinuclear region of cytoplasm GO:0048471 IEA
    presynapse GO:0098793 IEA
 Experiment description of studies that identified SNAP47 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SNAP47
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 F11R 50848
Two-hybrid Homo sapiens
3 GJD3  
Proximity Label-MS Homo sapiens
4 KRT73 319101
Affinity Capture-MS Homo sapiens
5 MTCH1 23787
Proximity Label-MS Homo sapiens
6 BLOC1S6  
Affinity Capture-MS Homo sapiens
7 METTL7A 25840
Proximity Label-MS Homo sapiens
8 LAMP3  
Proximity Label-MS Homo sapiens
9 ATG9A 79065
Proximity Label-MS Homo sapiens
10 GJA1 2697
Proximity Label-MS Homo sapiens
11 KLC3  
Two-hybrid Homo sapiens
12 FAM9B  
Two-hybrid Homo sapiens
13 TNFRSF8 943
Affinity Capture-MS Homo sapiens
14 HSD17B11 51170
Proximity Label-MS Homo sapiens
15 LAMP2 3920
Proximity Label-MS Homo sapiens
16 DNAJC25 548645
Proximity Label-MS Homo sapiens
17 CLEC12A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 STX4 6810
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
19 FIS1 51024
Proximity Label-MS Homo sapiens
20 STX1A 6804
Two-hybrid Homo sapiens
21 CEP57L1  
Two-hybrid Homo sapiens
22 LIME1 54923
Two-hybrid Homo sapiens
23 RAB3B 5865
Proximity Label-MS Homo sapiens
24 APOC4  
Two-hybrid Homo sapiens
25 STX8 9482
Affinity Capture-MS Homo sapiens
26 MAGEA6  
Two-hybrid Homo sapiens
27 STX7 8417
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 OIP5  
Affinity Capture-MS Homo sapiens
29 SSR1 6745
Proximity Label-MS Homo sapiens
30 MARCH5  
Proximity Label-MS Homo sapiens
31 STX18 53407
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 GGA1 26088
Affinity Capture-MS Homo sapiens
33 MID2 11043
Two-hybrid Homo sapiens
34 EXD2  
Proximity Label-MS Homo sapiens
35 STX6 10228
Proximity Label-MS Homo sapiens
36 SLC25A46 91137
Proximity Label-MS Homo sapiens
37 RAB35 11021
Proximity Label-MS Homo sapiens
38 SLC31A1 1317
Affinity Capture-MS Homo sapiens
39 EBAG9 9166
Proximity Label-MS Homo sapiens
40 APOC2 344
Two-hybrid Homo sapiens
41 STX12 23673
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 MARCKS 4082
Proximity Label-MS Homo sapiens
43 LAMTOR1 55004
Proximity Label-MS Homo sapiens
44 TRIM59  
Two-hybrid Homo sapiens
45 GOLGA2 2801
Two-hybrid Homo sapiens
46 KIAA1715 80856
Proximity Label-MS Homo sapiens
47 APOO 79135
Proximity Label-MS Homo sapiens
48 SPAG5 10615
Two-hybrid Homo sapiens
49 MTCH2 23788
Proximity Label-MS Homo sapiens
50 EMD 2010
Proximity Label-MS Homo sapiens
51 CXADR 1525
Proximity Label-MS Homo sapiens
52 FAM9C  
Affinity Capture-MS Homo sapiens
53 LYN 4067
Proximity Label-MS Homo sapiens
54 RAB4A 5867
Proximity Label-MS Homo sapiens
55 DIABLO 56616
Proximity Label-MS Homo sapiens
56 PDE3A  
Affinity Capture-MS Homo sapiens
57 OPA1 4976
Proximity Label-MS Homo sapiens
58 RPN1 6184
Proximity Label-MS Homo sapiens
59 RHOT2 89941
Proximity Label-MS Homo sapiens
60 ELOVL5 60481
Proximity Label-MS Homo sapiens
61 SEC61B 10952
Proximity Label-MS Homo sapiens
62 RMDN3 55177
Proximity Label-MS Homo sapiens
63 REEP5 7905
Proximity Label-MS Homo sapiens
64 AQP2 359
Two-hybrid Homo sapiens
65 RPN2 6185
Proximity Label-MS Homo sapiens
66 LRRC59 55379
Proximity Label-MS Homo sapiens
67 PANX1 24145
Proximity Label-MS Homo sapiens
68 RNF170 81790
Two-hybrid Homo sapiens
69 LAMP1 3916
Proximity Label-MS Homo sapiens
70 BCAP31 10134
Proximity Label-MS Homo sapiens
71 HSD3B7 80270
Proximity Label-MS Homo sapiens
72 CUL3 8452
Affinity Capture-MS Homo sapiens
73 STIM1 6786
Proximity Label-MS Homo sapiens
74 FKBP8 23770
Proximity Label-MS Homo sapiens
75 LRRC4C  
Two-hybrid Homo sapiens
76 ARF6 382
Proximity Label-MS Homo sapiens
77 OCIAD1 54940
Proximity Label-MS Homo sapiens
78 Max  
Affinity Capture-MS Mus musculus
79 KCNE3  
Affinity Capture-MS Homo sapiens
80 CCDC155  
Two-hybrid Homo sapiens
81 ATP2A1 487
Proximity Label-MS Homo sapiens
82 PTPN1 5770
Proximity Label-MS Homo sapiens
83 RAB9A 9367
Proximity Label-MS Homo sapiens
84 B3GAT1  
Proximity Label-MS Homo sapiens
85 NAPG 8774
Affinity Capture-MS Homo sapiens
86 MFN2 9927
Proximity Label-MS Homo sapiens
87 RHOB 388
Proximity Label-MS Homo sapiens
88 HAX1  
Proximity Label-MS Homo sapiens
89 FATE1  
Two-hybrid Homo sapiens
90 PEX3 8504
Proximity Label-MS Homo sapiens
91 AKAP1 8165
Proximity Label-MS Homo sapiens
92 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
93 USE1 55850
Affinity Capture-MS Homo sapiens
94 VAMP4 8674
Affinity Capture-MS Homo sapiens
95 C15orf59  
Affinity Capture-MS Homo sapiens
96 ERGIC1 57222
Proximity Label-MS Homo sapiens
97 C11orf52 91894
Proximity Label-MS Homo sapiens
98 ECHDC1 55862
Affinity Capture-MS Homo sapiens
99 BRK1 55845
Affinity Capture-MS Homo sapiens
100 PXMP2  
Proximity Label-MS Homo sapiens
101 RAB5A 5868
Proximity Label-MS Homo sapiens
102 ERGIC2 51290
Proximity Label-MS Homo sapiens
103 RAB2A 5862
Proximity Label-MS Homo sapiens
104 SEC62 7095
Proximity Label-MS Homo sapiens
105 STX3 6809
Affinity Capture-MS Homo sapiens
106 RAB7A 7879
Proximity Label-MS Homo sapiens
107 RAB11A 8766
Proximity Label-MS Homo sapiens
108 EPHA2 1969
Proximity Label-MS Homo sapiens
109 VAMP5 10791
Affinity Capture-MS Homo sapiens
110 DNAJC1 64215
Proximity Label-MS Homo sapiens
111 KRAS 3845
Proximity Label-MS Homo sapiens
112 RAB5C 5878
Proximity Label-MS Homo sapiens
113 CKAP4 10970
Proximity Label-MS Homo sapiens
114 CAV1 857
Proximity Label-MS Homo sapiens
115 LURAP1  
Affinity Capture-MS Homo sapiens
116 MGST3 4259
Two-hybrid Homo sapiens
117 DERL1 79139
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SNAP47 is involved
No pathways found





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