Gene description for TNFRSF8
Gene name
tumor necrosis factor receptor superfamily, member 8
Gene symbol
TNFRSF8
Other names/aliases
CD30 D1S166E Ki-1
Species
Homo sapiens
Database cross references - TNFRSF8
ExoCarta
ExoCarta_943
Entrez Gene
943
HGNC
11923
MIM
153243
UniProt
P28908
TNFRSF8 identified in exosomes derived from the following tissue/cell type
B cells
20458337
B cells
20458337
B cells
20458337
Gene ontology annotations for TNFRSF8
Experiment description of studies that identified TNFRSF8 in exosomes
1
Experiment ID
79
ISEV standards
✘
EV Biophysical techniques
✘
EV Cytosolic markers
✔
CD81|MHCII
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20458337
Organism
Homo sapiens
Experiment description
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W.
Journal name
ICB
Publication year
2010
Sample
B cells
Sample name
RN (HLA-DR15)
Isolation/purification methods
Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [FT-ICR] Western blotting
2
Experiment ID
80
ISEV standards
✘
EV Biophysical techniques
✘
EV Cytosolic markers
✔
CD81|MHCII
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20458337
Organism
Homo sapiens
Experiment description
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W.
Journal name
ICB
Publication year
2010
Sample
B cells
Sample name
RN (HLA-DR15)
Isolation/purification methods
Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [FT-ICR] Western blotting
3
Experiment ID
81
ISEV standards
✘
EV Biophysical techniques
✘
EV Cytosolic markers
✔
CD81|MHCII
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20458337
Organism
Homo sapiens
Experiment description
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W.
Journal name
ICB
Publication year
2010
Sample
B cells
Sample name
RN (HLA-DR15)
Isolation/purification methods
Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [FT-ICR] Western blotting
Protein-protein interactions for TNFRSF8
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
TNFSF8
Reconstituted Complex
Homo sapiens
2
TDP2
51567
Affinity Capture-Western
Homo sapiens
3
TRAF2
Invivo
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
4
TRAF1
7185
Invivo
Homo sapiens
5
TRIP
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
6
TRAF5
Invivo
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
7
TRAF3
7187
Invivo
Homo sapiens
View the network
image/svg+xml
Pathways in which TNFRSF8 is involved
No pathways found