Gene description for IGLC1
Gene name
immunoglobulin lambda constant 1 (Mcg marker)
Gene symbol
IGLC1
Other names/aliases
IGLC
Species
Homo sapiens
Database cross references - IGLC1
ExoCarta
ExoCarta_3537
Vesiclepedia
VP_3537
Entrez Gene
3537
HGNC
5855
MIM
147220
IGLC1 identified in exosomes derived from the following tissue/cell type
Breast milk
17641064
Mesenchymal stem cells
Unpublished / Not applicable
Platelets
25332113
Platelets
25332113
Platelets
25332113
Gene ontology annotations for IGLC1
Experiment description of studies that identified IGLC1 in exosomes
1
Experiment ID
46
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
HSC70|CD63|MHCII|CD81|CD86
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
17641064
Organism
Homo sapiens
Experiment description
Exosomes with immune modulatory features are present in human breast milk.
Authors
"Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S"
Journal name
JIMMU
Publication year
2007
Sample
Breast milk
Sample name
Breast milk - Colostrum
Isolation/purification methods
Differential centrifugation Filtration Sucrose density gradient
Flotation density
1.10-1.18 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [QSTAR] Western blotting Immunoelectron Microscopy FACS
2
Experiment ID
126
MISEV standards
✘
Biophysical techniques
✔
GAPDH
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry [LTQ-FT Ultra]
PubMed ID
Unpublished / Not applicable
Organism
Homo sapiens
Experiment description
Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors
"Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name
Mesenchymal Stem Cell Therapy
Publication year
2011
Sample
Mesenchymal stem cells
Sample name
huES9.E1
Isolation/purification methods
HPLC
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Antobody array Mass spectrometry
3
Experiment ID
231
MISEV standards
✘
Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein Lipids
Methods used in the study
Western blotting Mass spectrometry
4
Experiment ID
232
MISEV standards
✘
Biophysical techniques
✘
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
5
Experiment ID
233
MISEV standards
✘
Biophysical techniques
✘
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for IGLC1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
SERPINA1
5265
Affinity Capture-MS
Homo sapiens
2
HBB
3043
Affinity Capture-MS
Homo sapiens
3
UBQLN4
56893
Two-hybrid
Homo sapiens
4
STATH
Affinity Capture-MS
Homo sapiens
5
DCD
117159
Affinity Capture-MS
Homo sapiens
6
WWOX
51741
Affinity Capture-MS
Homo sapiens
7
NTPCR
84284
Affinity Capture-MS
Homo sapiens
8
FOXO1
Affinity Capture-MS
Homo sapiens
9
WHSC1
7468
Affinity Capture-MS
Homo sapiens
10
PMM2
5373
Affinity Capture-MS
Homo sapiens
11
COL1A1
1277
Affinity Capture-MS
Homo sapiens
12
HCCS
3052
Affinity Capture-MS
Homo sapiens
13
HP
3240
Affinity Capture-MS
Homo sapiens
14
HR
Affinity Capture-MS
Homo sapiens
15
PHF23
79142
Affinity Capture-MS
Homo sapiens
16
PRR4
11272
Affinity Capture-MS
Homo sapiens
17
CUL7
9820
Affinity Capture-MS
Homo sapiens
18
LCN1
3933
Affinity Capture-MS
Homo sapiens
19
SGTA
6449
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
20
UBQLN1
29979
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
21
PAX3
Affinity Capture-MS
Homo sapiens
22
L3MBTL4
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which IGLC1 is involved
No pathways found