Gene description for GABRB3
Gene name
gamma-aminobutyric acid (GABA) A receptor, beta 3
Gene symbol
GABRB3
Other names/aliases
ECA5
Species
Homo sapiens
Database cross references - GABRB3
ExoCarta
ExoCarta_2562
Vesiclepedia
VP_2562
Entrez Gene
2562
HGNC
4083
MIM
137192
UniProt
P28472
GABRB3 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells
26054723
Hepatocellular carcinoma cells
26054723
Gene ontology annotations for GABRB3
Experiment description of studies that identified GABRB3 in exosomes
1
Experiment ID
234
MISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Enriched markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-C3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
235
MISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Enriched markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
Protein-protein interactions for GABRB3
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
PRKCA
5578
Reconstituted Complex
Homo sapiens
2
PRKACA
5566
Reconstituted Complex
Homo sapiens
3
AKAP5
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
View the network
image/svg+xml
Pathways in which GABRB3 is involved