Gene description for AFG3L2
Gene name AFG3-like AAA ATPase 2
Gene symbol AFG3L2
Other names/aliases SCA28
SPAX5
Species Homo sapiens
 Database cross references - AFG3L2
ExoCarta ExoCarta_10939
Vesiclepedia VP_10939
Entrez Gene 10939
HGNC 315
MIM 604581
UniProt Q9Y4W6  
 AFG3L2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
 Gene ontology annotations for AFG3L2
Molecular Function
    DNA clamp loader activity GO:0003689 IEA
    ATP-dependent peptidase activity GO:0004176 IEA
    metalloendopeptidase activity GO:0004222 IBA
    metalloendopeptidase activity GO:0004222 IDA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    metallopeptidase activity GO:0008237 IMP
    zinc ion binding GO:0008270 IEA
    ATP hydrolysis activity GO:0016887 IDA
    unfolded protein binding GO:0051082 TAS
    cohesin loader activity GO:0061775 IEA
    chromatin extrusion motor activity GO:0140584 IEA
    ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA
    ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA
Biological Process
    chromatin remodeling GO:0006338 IEA
    proteolysis GO:0006508 IDA
    proteolysis GO:0006508 IMP
    axonogenesis GO:0007409 IMP
    neuromuscular junction development GO:0007528 IEA
    mitochondrial fusion GO:0008053 IEA
    protein processing GO:0016485 ISS
    protein autoprocessing GO:0016540 ISS
    nerve development GO:0021675 IEA
    protein catabolic process GO:0030163 IDA
    membrane protein proteolysis GO:0033619 IDA
    mitochondrial protein processing GO:0034982 IBA
    calcium import into the mitochondrion GO:0036444 IMP
    regulation of multicellular organism growth GO:0040014 IEA
    cristae formation GO:0042407 IEA
    myelination GO:0042552 IEA
    mitochondrial calcium ion homeostasis GO:0051560 IMP
    protein maturation GO:0051604 IDA
    muscle cell development GO:0055001 IEA
    righting reflex GO:0060013 IEA
    cellular response to glutathione GO:0072753 IDA
    regulation of calcium import into the mitochondrion GO:0110097 IDA
    chromatin looping GO:0140588 IEA
    mitochondrial protein quality control GO:0141164 IDA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial inner membrane GO:0005743 ISS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial inner membrane GO:0005743 TAS
    m-AAA complex GO:0005745 IBA
    m-AAA complex GO:0005745 IDA
 Experiment description of studies that identified AFG3L2 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for AFG3L2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 C15orf39  
Affinity Capture-MS Homo sapiens
3 RIT1 6016
Negative Genetic Homo sapiens
4 SLIRP 81892
Proximity Label-MS Homo sapiens
5 ZFHX4  
Affinity Capture-MS Homo sapiens
6 MRPS26 64949
Proximity Label-MS Homo sapiens
7 MTCH1 23787
Proximity Label-MS Homo sapiens
8 NDUFS1 4719
Co-fractionation Homo sapiens
9 COX15 1355
Proximity Label-MS Homo sapiens
10 SPRTN  
Affinity Capture-MS Homo sapiens
11 CSNK1A1 1452
Affinity Capture-MS Homo sapiens
12 TGS1  
Affinity Capture-MS Homo sapiens
13 TRUB2  
Proximity Label-MS Homo sapiens
14 MTG2  
Proximity Label-MS Homo sapiens
15 NGRN  
Proximity Label-MS Homo sapiens
16 SPTLC1 10558
Affinity Capture-MS Homo sapiens
17 Hspa14 50497
Affinity Capture-MS Mus musculus
18 ZZZ3  
Affinity Capture-MS Homo sapiens
19 GJD3  
Proximity Label-MS Homo sapiens
20 NDUFA4 4697
Affinity Capture-MS Homo sapiens
21 HSD17B12 51144
Co-fractionation Homo sapiens
22 MTRF1  
Proximity Label-MS Homo sapiens
23 GFM2 84340
Proximity Label-MS Homo sapiens
24 SUPV3L1 6832
Affinity Capture-MS Homo sapiens
25 CCDC90B  
Proximity Label-MS Homo sapiens
26 LRPPRC 10128
Proximity Label-MS Homo sapiens
27 KIAA1429 25962
Affinity Capture-MS Homo sapiens
28 C9orf78 51759
Affinity Capture-MS Homo sapiens
29 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
30 TIMMDC1  
Affinity Capture-MS Homo sapiens
31 MCU 90550
Proximity Label-MS Homo sapiens
32 CRYZ 1429
Proximity Label-MS Homo sapiens
33 TFAM 7019
Proximity Label-MS Homo sapiens
34 TBX3 6926
Affinity Capture-MS Homo sapiens
35 PMPCA 23203
Proximity Label-MS Homo sapiens
36 COQ9  
Affinity Capture-MS Homo sapiens
37 HINT2 84681
Proximity Label-MS Homo sapiens
38 PTPMT1 114971
Affinity Capture-MS Homo sapiens
39 CHCHD2  
Affinity Capture-MS Homo sapiens
40 WBSCR16  
Proximity Label-MS Homo sapiens
41 FBXW7  
Affinity Capture-MS Homo sapiens
42 C8orf82  
Proximity Label-MS Homo sapiens
43 MAGEA6  
Affinity Capture-MS Homo sapiens
44 SLC25A12 8604
Proximity Label-MS Homo sapiens
45 MAD2L2 10459
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 C11orf52 91894
Proximity Label-MS Homo sapiens
47 Cenpe  
Affinity Capture-MS Mus musculus
48 SURF1  
Proximity Label-MS Homo sapiens
49 Kctd5  
Affinity Capture-MS Mus musculus
50 APP 351
Reconstituted Complex Homo sapiens
51 EXD2  
Proximity Label-MS Homo sapiens
52 RC3H1 149041
Affinity Capture-MS Homo sapiens
53 SLC25A46 91137
Proximity Label-MS Homo sapiens
54 DNAJC7 7266
Proximity Label-MS Homo sapiens
55 PHB 5245
Co-fractionation Homo sapiens
56 MAVS 57506
Proximity Label-MS Homo sapiens
57 PMPCB 9512
Proximity Label-MS Homo sapiens
58 NDUFA11 126328
Affinity Capture-MS Homo sapiens
59 FASTKD2  
Proximity Label-MS Homo sapiens
60 VWA8 23078
Proximity Label-MS Homo sapiens
61 UQCRQ 27089
Co-fractionation Homo sapiens
62 SLC25A3 5250
Co-fractionation Homo sapiens
63 KIF14 9928
Affinity Capture-MS Homo sapiens
64 GBA2  
Affinity Capture-MS Homo sapiens
65 MAPK8IP2  
Two-hybrid Homo sapiens
66 LMAN1 3998
Proximity Label-MS Homo sapiens
67 MDH2 4191
Proximity Label-MS Homo sapiens
68 NUP155 9631
Proximity Label-MS Homo sapiens
69 APOO 79135
Proximity Label-MS Homo sapiens
70 CTNNA1 1495
Proximity Label-MS Homo sapiens
71 NF2 4771
Affinity Capture-MS Homo sapiens
72 MTCH2 23788
Proximity Label-MS Homo sapiens
73 C6orf203  
Proximity Label-MS Homo sapiens
74 SLC1A5 6510
Affinity Capture-MS Homo sapiens
75 MAGEA2  
Affinity Capture-MS Homo sapiens
76 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
77 ATP1A1 476
Co-fractionation Homo sapiens
78 FASTKD5  
Proximity Label-MS Homo sapiens
79 METTL15  
Proximity Label-MS Homo sapiens
80 PARK2  
Affinity Capture-MS Homo sapiens
81 TBX2  
Affinity Capture-MS Homo sapiens
82 Trip11  
Affinity Capture-MS Mus musculus
83 HSCB 150274
Proximity Label-MS Homo sapiens
84 TUFM 7284
Proximity Label-MS Homo sapiens
85 INPPL1 3636
Affinity Capture-MS Homo sapiens
86 DIABLO 56616
Proximity Label-MS Homo sapiens
87 PEX3 8504
Proximity Label-MS Homo sapiens
88 DNAJC5 80331
Proximity Label-MS Homo sapiens
89 TBC1D32 221322
Proximity Label-MS Homo sapiens
90 TUBA1C 84790
Affinity Capture-MS Homo sapiens
91 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
92 DIRAS3  
Proximity Label-MS Homo sapiens
93 NTRK1 4914
Affinity Capture-MS Homo sapiens
94 CCDC109B 55013
Proximity Label-MS Homo sapiens
95 PDP2  
Affinity Capture-MS Homo sapiens
96 TBRG4 9238
Proximity Label-MS Homo sapiens
97 CYC1 1537
Co-fractionation Homo sapiens
98 DHFRL1  
Proximity Label-MS Homo sapiens
99 Bmpr1a  
Affinity Capture-MS Mus musculus
100 MRPL11 65003
Proximity Label-MS Homo sapiens
101 MTRF1L  
Proximity Label-MS Homo sapiens
102 DNAJC30  
Proximity Label-MS Homo sapiens
103 AHCTF1 25909
Affinity Capture-MS Homo sapiens
104 RHOT2 89941
Proximity Label-MS Homo sapiens
105 TMEM70  
Proximity Label-MS Homo sapiens
106 SEC61B 10952
Proximity Label-MS Homo sapiens
107 CYLD  
Affinity Capture-MS Homo sapiens
108 COX4I1 1327
Proximity Label-MS Homo sapiens
109 ELL2 22936
Affinity Capture-MS Homo sapiens
110 CISD3 284106
Affinity Capture-MS Homo sapiens
111 TEFM  
Proximity Label-MS Homo sapiens
112 DST 667
Affinity Capture-MS Homo sapiens
113 SLC16A1 6566
Affinity Capture-MS Homo sapiens
114 C15orf48  
Affinity Capture-MS Homo sapiens
115 OTC 5009
Proximity Label-MS Homo sapiens
116 HSD3B7 80270
Proximity Label-MS Homo sapiens
117 CLN3 1201
Affinity Capture-MS Homo sapiens
118 AK2 204
Co-fractionation Homo sapiens
119 MRRF  
Proximity Label-MS Homo sapiens
120 AIFM1 9131
Proximity Label-MS Homo sapiens
121 MRPS12  
Proximity Label-MS Homo sapiens
122 MTIF2 4528
Proximity Label-MS Homo sapiens
123 NDUFA13 51079
Affinity Capture-MS Homo sapiens
124 PTEN 5728
Affinity Capture-MS Homo sapiens
125 NDUFA9 4704
Co-fractionation Homo sapiens
126 RC3H2  
Affinity Capture-MS Homo sapiens
127 MTFMT  
Proximity Label-MS Homo sapiens
128 CLPP 8192
Proximity Label-MS Homo sapiens
129 MTIF3  
Proximity Label-MS Homo sapiens
130 UQCRC2 7385
Co-fractionation Homo sapiens
131 C2orf47  
Affinity Capture-MS Homo sapiens
132 ATG12  
Proximity Label-MS Homo sapiens
133 SAMM50 25813
Proximity Label-MS Homo sapiens
134 CUL3 8452
Affinity Capture-MS Homo sapiens
135 ATP5F1 515
Co-fractionation Homo sapiens
136 RMND1 55005
Proximity Label-MS Homo sapiens
137 EGFR 1956
Affinity Capture-MS Homo sapiens
138 FKBP8 23770
Proximity Label-MS Homo sapiens
139 ARF6 382
Proximity Label-MS Homo sapiens
140 FBXO6 26270
Affinity Capture-MS Homo sapiens
141 DHX30 22907
Proximity Label-MS Homo sapiens
142 RIPK4  
Affinity Capture-MS Homo sapiens
143 SUZ12  
Affinity Capture-MS Homo sapiens
144 OCIAD1 54940
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
145 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
146 GRSF1 2926
Proximity Label-MS Homo sapiens
147 C12orf65  
Proximity Label-MS Homo sapiens
148 EPHA2 1969
Proximity Label-MS Homo sapiens
149 TACO1  
Proximity Label-MS Homo sapiens
150 MTG1  
Proximity Label-MS Homo sapiens
151 RPUSD4 84881
Proximity Label-MS Homo sapiens
152 RPA3 6119
Proximity Label-MS Homo sapiens
153 APOOL 139322
Affinity Capture-MS Homo sapiens
154 TMCO1 54499
Co-fractionation Homo sapiens
155 TSFM 10102
Proximity Label-MS Homo sapiens
156 USP50  
Affinity Capture-MS Homo sapiens
157 ACAD9 28976
Proximity Label-MS Homo sapiens
158 RPN1 6184
Co-fractionation Homo sapiens
159 Junb  
Affinity Capture-MS Mus musculus
160 DDRGK1 65992
Affinity Capture-MS Homo sapiens
161 RNF2  
Affinity Capture-MS Homo sapiens
162 CLPB 81570
Proximity Label-MS Homo sapiens
163 HAX1  
Proximity Label-MS Homo sapiens
164 MAGEA12  
Affinity Capture-MS Homo sapiens
165 HSPA9 3313
Proximity Label-MS Homo sapiens
166 AUH 549
Proximity Label-MS Homo sapiens
167 RAC2 5880
Two-hybrid Homo sapiens
168 DNAJC15  
Proximity Label-MS Homo sapiens
169 AKAP1 8165
Proximity Label-MS Homo sapiens
170 MCUR1 63933
Proximity Label-MS Homo sapiens
171 FLOT1 10211
Proximity Label-MS Homo sapiens
172 CCDC8  
Affinity Capture-MS Homo sapiens
173 ACBD5 91452
Proximity Label-MS Homo sapiens
174 HIPK4  
Affinity Capture-MS Homo sapiens
175 PAM16  
Affinity Capture-MS Homo sapiens
176 BTK 695
Affinity Capture-MS Homo sapiens
177 DNAJC4  
Proximity Label-MS Homo sapiens
178 MTERF3  
Proximity Label-MS Homo sapiens
179 DNAJC28  
Proximity Label-MS Homo sapiens
180 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
181 CCDC58 131076
Affinity Capture-MS Homo sapiens
182 C17orf80 55028
Proximity Label-MS Homo sapiens
183 PHB2 11331
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
184 Tubg1 103733
Affinity Capture-MS Mus musculus
185 RBM45  
Affinity Capture-MS Homo sapiens
186 LAMTOR1 55004
Proximity Label-MS Homo sapiens
187 DNAJC19 131118
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
188 FBXL6  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
189 CHCHD1  
Proximity Label-MS Homo sapiens
190 MACF1 23499
Affinity Capture-MS Homo sapiens
191 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
192 MFSD4  
Affinity Capture-MS Homo sapiens
193 LONP1 9361
Proximity Label-MS Homo sapiens
194 HSD17B11 51170
Proximity Label-MS Homo sapiens
195 PDHA1 5160
Proximity Label-MS Homo sapiens
196 LCK 3932
Proximity Label-MS Homo sapiens
197 DNAJA3 9093
Proximity Label-MS Homo sapiens
198 COX8A  
Proximity Label-MS Homo sapiens
199 CHD4 1108
Affinity Capture-MS Homo sapiens
200 MICU1 10367
Affinity Capture-MS Homo sapiens
201 C21orf33  
Proximity Label-MS Homo sapiens
202 SSBP1 6742
Proximity Label-MS Homo sapiens
203 SFXN1 94081
Proximity Label-MS Homo sapiens
204 ANAPC2 29882
Proximity Label-MS Homo sapiens
205 UFL1 23376
Affinity Capture-MS Homo sapiens
206 PXMP2  
Proximity Label-MS Homo sapiens
207 FASTKD3  
Proximity Label-MS Homo sapiens
208 UBB 7314
Affinity Capture-MS Homo sapiens
209 COQ2  
Affinity Capture-MS Homo sapiens
210 NDUFS8 4728
Co-fractionation Homo sapiens
211 GFM1 85476
Proximity Label-MS Homo sapiens
212 BECN1 8678
Affinity Capture-MS Homo sapiens
213 AARS2  
Proximity Label-MS Homo sapiens
214 FIS1 51024
Proximity Label-MS Homo sapiens
215 NEDD1 121441
Affinity Capture-MS Homo sapiens
216 RAD21 5885
Affinity Capture-MS Homo sapiens
217 C19orf52  
Proximity Label-MS Homo sapiens
218 SLC25A51  
Proximity Label-MS Homo sapiens
219 RAB11A 8766
Proximity Label-MS Homo sapiens
220 RPUSD3  
Proximity Label-MS Homo sapiens
221 BRD1 23774
Affinity Capture-MS Homo sapiens
222 C1QBP 708
Proximity Label-MS Homo sapiens
223 Tnpo1 238799
Affinity Capture-MS Mus musculus
224 KRAS 3845
Negative Genetic Homo sapiens
225 C9orf72  
Affinity Capture-MS Homo sapiens
226 PHC2  
Two-hybrid Homo sapiens
227 USF1  
Affinity Capture-MS Homo sapiens
228 METTL17  
Proximity Label-MS Homo sapiens
229 SEC61A1 29927
Affinity Capture-MS Homo sapiens
230 PEX14 5195
Proximity Label-MS Homo sapiens
231 Smn1 20595
Affinity Capture-MS Mus musculus
232 DDX28  
Proximity Label-MS Homo sapiens
233 CUL4A 8451
Affinity Capture-MS Homo sapiens
234 ATP5A1 498
Co-fractionation Homo sapiens
235 RNF139  
Affinity Capture-MS Homo sapiens
236 INTU  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here