Gene description for NDUFA11
Gene name NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
Gene symbol NDUFA11
Other names/aliases B14.7
CI-B14.7
Species Homo sapiens
 Database cross references - NDUFA11
ExoCarta ExoCarta_126328
Vesiclepedia VP_126328
Entrez Gene 126328
HGNC 20371
MIM 612638
UniProt Q86Y39  
 NDUFA11 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for NDUFA11
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    aerobic respiration GO:0009060 NAS
    mitochondrial respiratory chain complex I assembly GO:0032981 IMP
    proton motive force-driven mitochondrial ATP synthesis GO:0042776 NAS
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 ISS
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial inner membrane GO:0005743 TAS
    respiratory chain complex I GO:0045271 IBA
    respiratory chain complex I GO:0045271 IDA
 Experiment description of studies that identified NDUFA11 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for NDUFA11
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NDUFV1 4723
Affinity Capture-MS Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 NDUFV3 4731
Affinity Capture-MS Homo sapiens
4 AFG3L2 10939
Affinity Capture-MS Homo sapiens
5 C15orf48  
Affinity Capture-MS Homo sapiens
6 MRPL44  
Affinity Capture-MS Homo sapiens
7 COX5B 1329
Affinity Capture-MS Homo sapiens
8 NDUFA6  
Affinity Capture-MS Homo sapiens
9 NDUFS1 4719
Affinity Capture-MS Homo sapiens
10 SLC25A12 8604
Proximity Label-MS Homo sapiens
11 NDUFS5 4725
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 TP53 7157
Affinity Capture-MS Homo sapiens
13 NDUFA9 4704
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 ND5 4540
Affinity Capture-MS Homo sapiens
15 TMEM14C 51522
Co-fractionation Homo sapiens
16 NDUFB5 4711
Affinity Capture-MS Homo sapiens
17 FOXC1  
Affinity Capture-MS Homo sapiens
18 NDUFS4 4724
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 UQCRB 7381
Affinity Capture-MS Homo sapiens
20 NDUFA12 55967
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 UQCR10 29796
Affinity Capture-MS Homo sapiens
22 GAA 2548
Affinity Capture-MS Homo sapiens
23 ND2 4536
Affinity Capture-MS Homo sapiens
24 GHITM 27069
Affinity Capture-MS Homo sapiens
25 NDUFA8 4702
Affinity Capture-MS Homo sapiens
26 UFL1 23376
Affinity Capture-MS Homo sapiens
27 DUSP12 11266
Affinity Capture-MS Homo sapiens
28 NDUFS8 4728
Affinity Capture-MS Homo sapiens
29 NDUFS3 4722
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 YME1L1 10730
Affinity Capture-MS Homo sapiens
31 NDUFB3 4709
Affinity Capture-MS Homo sapiens
32 NDUFB8 4714
Affinity Capture-MS Homo sapiens
33 PCK1 5105
Affinity Capture-MS Homo sapiens
34 NIT1 4817
Affinity Capture-MS Homo sapiens
35 NDUFB6 4712
Affinity Capture-MS Homo sapiens
36 NDUFA2 4695
Affinity Capture-MS Homo sapiens
37 MEOX2  
Two-hybrid Homo sapiens
38 SERBP1 26135
Affinity Capture-MS Homo sapiens
39 NDUFAB1 4706
Affinity Capture-MS Homo sapiens
40 NDUFA5 4698
Affinity Capture-MS Homo sapiens
41 DUSP21  
Affinity Capture-MS Homo sapiens
42 NDUFB11 54539
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 NDUFA10 4705
Affinity Capture-MS Homo sapiens
44 NDUFV2 4729
Affinity Capture-MS Homo sapiens
45 UQCRFS1 7386
Affinity Capture-MS Homo sapiens
46 ND4 4538
Affinity Capture-MS Homo sapiens
47 NDUFS6  
Affinity Capture-MS Homo sapiens
48 C9orf72  
Affinity Capture-MS Homo sapiens
49 NDUFS2 4720
Affinity Capture-MS Homo sapiens
50 NDUFS7 374291
Affinity Capture-MS Homo sapiens
51 NDUFB4 4710
Affinity Capture-MS Homo sapiens
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