Gene description for UQCR10
Gene name ubiquinol-cytochrome c reductase, complex III subunit X
Gene symbol UQCR10
Other names/aliases HSPC051
HSPC119
HSPC151
QCR9
UCCR7.2
UCRC
Species Homo sapiens
 Database cross references - UQCR10
ExoCarta ExoCarta_29796
Vesiclepedia VP_29796
Entrez Gene 29796
HGNC 30863
MIM 610843
UniProt Q9UDW1  
 UQCR10 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for UQCR10
Molecular Function
    protein binding GO:0005515 IPI
    ubiquinol-cytochrome-c reductase activity GO:0008121 NAS
Biological Process
    mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 IBA
    mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 NAS
    cellular respiration GO:0045333 NAS
    proton transmembrane transport GO:1902600 IEA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial inner membrane GO:0005743 TAS
    respiratory chain complex III GO:0045275 IBA
 Experiment description of studies that identified UQCR10 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for UQCR10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GPM6A 2823
Affinity Capture-MS Homo sapiens
2 C15orf48  
Affinity Capture-MS Homo sapiens
3 CYSTM1 84418
Co-fractionation Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 NDUFA11 126328
Affinity Capture-MS Homo sapiens
6 UQCRQ 27089
Affinity Capture-MS Homo sapiens
7 NDUFA9 4704
Affinity Capture-MS Homo sapiens
8 PEX19 5824
Affinity Capture-MS Homo sapiens
9 E2F4  
Affinity Capture-MS Homo sapiens
10 UQCRC2 7385
Affinity Capture-MS Homo sapiens
11 KPNB1 3837
Affinity Capture-MS Homo sapiens
12 FOXA1  
Affinity Capture-MS Homo sapiens
13 HNRNPM 4670
Co-fractionation Homo sapiens
14 UQCRB 7381
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 COX6B1 1340
Affinity Capture-MS Homo sapiens
16 ERBB3 2065
Affinity Capture-MS Homo sapiens
17 DDX58 23586
Affinity Capture-RNA Homo sapiens
18 PTGES2 80142
Affinity Capture-MS Homo sapiens
19 UFL1 23376
Affinity Capture-MS Homo sapiens
20 KIAA1429 25962
Affinity Capture-MS Homo sapiens
21 S100A4 6275
Affinity Capture-MS Homo sapiens
22 TMED10 10972
Affinity Capture-MS Homo sapiens
23 NDUFS3 4722
Affinity Capture-MS Homo sapiens
24 RPA3 6119
Proximity Label-MS Homo sapiens
25 TSPAN6 7105
Affinity Capture-MS Homo sapiens
26 COX7A2L 9167
Affinity Capture-MS Homo sapiens
27 RAB11A 8766
Co-fractionation Homo sapiens
28 TIMMDC1  
Affinity Capture-MS Homo sapiens
29 MOV10 4343
Co-fractionation Homo sapiens
Affinity Capture-RNA Homo sapiens
30 PRC1 9055
Affinity Capture-MS Homo sapiens
31 CYC1 1537
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 UQCRC1 7384
Affinity Capture-MS Homo sapiens
33 DDRGK1 65992
Affinity Capture-MS Homo sapiens
34 ABCB10 23456
Affinity Capture-MS Homo sapiens
35 SLC9A9 285195
Affinity Capture-MS Homo sapiens
36 KRAS 3845
Negative Genetic Homo sapiens
37 CYTB 4519
Affinity Capture-MS Homo sapiens
38 UQCRH 7388
Affinity Capture-MS Homo sapiens
39 UQCRFS1 7386
Affinity Capture-MS Homo sapiens
40 C9orf72  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here