Gene description for NIT1
Gene name nitrilase 1
Gene symbol NIT1
Other names/aliases -
Species Homo sapiens
 Database cross references - NIT1
ExoCarta ExoCarta_4817
Entrez Gene 4817
HGNC 7828
MIM 604618
UniProt Q86X76  
 NIT1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for NIT1
Molecular Function
    nitrilase activity GO:0000257 TAS
Biological Process
    biological_process GO:0008150 ND
    nitrogen compound metabolic process GO:0006807 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    extracellular exosome GO:0070062 IDA
    mitochondrion GO:0005739 IEA
 Experiment description of studies that identified NIT1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NIT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 XRCC6 2547
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which NIT1 is involved
No pathways found





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